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An integration of complementary strategies for gene-expression analysis to reveal novel therapeutic opportunities for breast cancer

Andrea H Bild1,2* email, Joel S Parker3,4* email, Adam M Gustafson5 email, Chaitanya R Acharya2 email, Katherine A Hoadley3,4 email, Carey Anders2 email, P Kelly Marcom2 email, Lisa A Carey3,7 email, Anil Potti2 email, Joseph R Nevins2 email and Charles M Perou3,4,6,8 email

Department of Pharmacology and Toxicology, University of Utah, 112 Skaggs Hall, Salt Lake City, UT 84112, USA

Duke Institute for Genome Sciences & Policy, Duke University Medical Center, 2121 CIEMAS, Durham, NC 27701, USA

Lineberger Comprehensive Cancer Center, University of North Carolina, 102 Mason Farm Road, Chapel Hill, NC 27599, USA

Department of Genetics, University of North Carolina, 120 Mason Farm Road, Chapel Hill, NC 27599, USA

The Pulmonary Center, Boston University School of Medicine, 715 Albany St, Boston, MA 02118, USA

Department of Pathology & Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599, USA

Division of Hematology/Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA

Carolina Center for Genome Sciences, 5016 Genetic Medicine Building, University of North Carolina, Chapel Hill, NC 27599, USA

author email corresponding author email* Contributed equally

Breast Cancer Research 2009, 11:R55doi:10.1186/bcr2344

Published: 28 July 2009

Additional files

Additional file 1:

A box-and-whisker plot showing pathway activation as a function of subtype displayed for an additional validation dataset.

Format: PDF Size: 315KB Download file

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