Identification of biology-based breast cancer types with distinct predictive and prognostic features: role of steroid hormone and HER2 receptor expression in patients treated with neoadjuvant anthracycline/taxane-based chemotherapy

Silvia Darb-Esfahani¹ , Sibylle Loibl² , Berit M Müller¹ , Marc Roller² , Carsten Denkert¹ , Martina Komor² , Karsten Schlüns¹ , Jens Uwe Blohmer³ , Jan Budczies¹ , Bernd Gerber⁴ , Aurelia Noske¹ , Andreas du Bois⁵ , Wilko Weichert¹ , Christian Jackisch⁶ , Manfred Dietel¹ , Klaus Richter⁷ , Manfred Kaufmann⁸ and Gunter von Minckwitz²

¹  Institute of Pathology, Charité Universitätsmedizin Berlin, Charitéplatz 1, Berlin, 10117, Germany

²  GBG Forschungs GmbH, Schleussnerstrasse 42, Neu-Isenburg, 63263, Germany

³  Department of Obstetrics and Gynecology, St. Gertrauden Hospital, Paretzer Str. 12, Berlin, 10713, Germany

⁴  Department of Obstetrics and Gynecology, Klinikum Südstadt, Südring 81, Rostock, 18059, Germany

⁵  Department of Gynecology and Gynecologic Oncology, Dr. Horst Schmidt Hospital (HSK), Ludwig-Erhard-Str. 100, Wiesbaden, 65199, Germany

⁶  Department of Obstetrics and Gynecology, Klinikum Offenbach, Starkenburgring 66, Offenbach am Main, 63069, Germany

⁷  Institute of Pathology, Berliner Allee 48, Hannover, 30175, Germany

⁸  Department of Obstetrics and Gynecology, Klinikum der Johann Wolofgang Goethe-Universität, Theodor-Stern-Kai 7, Frankfurt am Main, 60590, Germany