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Volume 11 Issue 6
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Comment |
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PARP inhibitors and the treatment of breast cancer: beyond BRCA1/2?
Kristine M Frizzell, W Lee Kraus Breast Cancer Research 2009, 11:111 (26 November 2009)
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CDK inhibitors as potential breast cancer therapeutics: new evidence for enhanced efficacy in ER+ disease
Robert L Sutherland, Elizabeth A Musgrove Breast Cancer Research 2009, 11:112 (7 December 2009)
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From normal cell types to malignant phenotypes
Özden Yalcin-Ozuysal, Cathrin Brisken Breast Cancer Research 2009, 11:306 (9 November 2009)
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Rah, rah, ROS: metabolic changes caused by loss of adhesion induce cell death
Christian D Young, Steven M Anderson Breast Cancer Research 2009, 11:307 (18 November 2009)
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Review |
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Epithelial to mesenchymal transition and breast cancer
Eva Tomaskovic-Crook, Erik W Thompson, Jean Thiery Breast Cancer Research 2009, 11:213 (9 November 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Research |
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Hes-6, an inhibitor of Hes-1, is regulated by 17β-estradiol and promotes breast cancer cell proliferation
Johan Hartman, Eric W-F Lam, Jan-Åke Gustafsson, Anders Ström Breast Cancer Research 2009, 11:R79 (5 November 2009)
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A selective eradication of human nonhereditary breast cancer cells by phenanthridine-derived polyADP-ribose polymerase inhibitors
Dana Inbar-Rozensal, Asher Castiel, Leonid Visochek, David Castel, Françoise Dantzer, Shai Izraeli, Malka Cohen-Armon Breast Cancer Research 2009, 11:R78 (9 November 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Phenanthridine derived polyADP-ribose polymerase (PARP) inhibitors originally designed to protect cells from cell-death under stress conditions efficiently eradicate breast cancer cells without impairing normal proliferating or non-proliferating cells.
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Altered serotonin physiology in human breast cancers favors paradoxical growth and cell survival
Vaibhav P Pai, Aaron M Marshall, Laura L Hernandez, Arthur R Buckley, Nelson D Horseman Breast Cancer Research 2009, 11:R81 (10 November 2009)
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Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: the UK MARIBS study
Deborah J Thompson, Martin O Leach, Gek Kwan-Lim, Simon A Gayther, Susan J Ramus, Iqbal Warsi, Fiona Lennard, Michael Khazen, Emilie Bryant, Sadie Reed, Caroline RM Boggis, D Gareth Evans, Rosalind A Eeles, Douglas F Easton, Ruth ML Warren, The UK study of MRI screening for breast cancer in women at high risk (MARIBS) Breast Cancer Research 2009, 11:R80 (11 November 2009)
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Dynamic regulation of CD24 and the invasive, CD44posCD24neg phenotype in breast cancer cell lines
Matthew J Meyer, Jodie M Fleming, Mustapha A Ali, Mitchell W Pesesky, Erika Ginsburg, Barbara K Vonderhaar Breast Cancer Research 2009, 11:R82 (11 November 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Ku proteins interact with activator protein-2 transcription factors and contribute to ERBB2 overexpression in breast cancer cell lines
Grégory Nolens, Jean-Christophe Pignon, Benjamin Koopmansch, Benaïssa Elmoualij, Willy Zorzi, Edwin De Pauw, Rosita Winkler Breast Cancer Research 2009, 11:R83 (11 November 2009)
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Hypoxia-inducible factor-1α and vascular endothelial growth factor expression in circulating tumor cells of breast cancer patients
Galatea Kallergi, Harris Markomanolaki, Vicky Giannoukaraki, Maria A Papadaki, Areti Strati, Evi S Lianidou, Vassilis Georgoulias, Dimitris Mavroudis, Sofia Agelaki Breast Cancer Research 2009, 11:R84 (17 November 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Declining recurrence among ductal carcinoma in situ patients treated with breast-conserving surgery in the community setting
Laurel A Habel, Ninah S Achacoso, Reina Haque, Larissa Nekhlyudov, Suzanne W Fletcher, Stuart J Schnitt, Laura C Collins, Ann M Geiger, Balaram Puligandla, Luana Acton, Charles P Quesenberry Breast Cancer Research 2009, 11:R85 (18 November 2009)
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Comprehensive characterization of the DNA amplification at 13q34 in human breast cancer reveals TFDP1 and CUL4A as likely candidate target genes
Lorenzo Melchor, Laura Paula Saucedo-Cuevas, Iván Muñoz-Repeto, Socorro María Rodríguez-Pinilla, Emiliano Honrado, Alfredo Campoverde, Jose Palacios, Katherine L Nathanson, María José García, Javier Benítez Breast Cancer Research 2009, 11:R86 (8 December 2009)
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Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy
Nancy Dumont, Yongping G Crawford, Mahvash Sigaroudinia, Shefali S Nagrani, Matthew B Wilson, Gertrude C Buehring, Gulisa Turashvili, Samuel Aparicio, Mona L Gauthier, Colleen A Fordyce, Kimberly M McDermott, Thea D Tlsty Breast Cancer Research 2009, 11:R87 (8 December 2009)
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Extent of differential allelic expression of candidate breast cancer genes is similar in blood and breast
Ana-Teresa Maia, Inmaculada Spiteri, Alvin JX Lee, Martin O'Reilly, Linda Jones, Carlos Caldas, Bruce AJ Ponder Breast Cancer Research 2009, 11:R88 (10 December 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Combined effects of single nucleotide polymorphisms TP53 R72P and MDM2 SNP309, and p53 expression on survival of breast cancer patients
Marjanka K Schmidt, Johanna Tommiska, Annegien Broeks, Flora E van Leeuwen, Laura J Van't Veer, Paul DP Pharoah, Douglas F Easton, Mitul Shah, Manjeet Humphreys, Thilo Dörk, Scarlett A Reincke, Rainer Fagerholm, Carl Blomqvist, Heli Nevanlinna Breast Cancer Research 2009, 11:R89 (18 December 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Investigating AP-2 and YY1 protein expression as a cause of high HER2 gene transcription in breast cancers with discordant HER2 gene amplification
Desmond G Powe, Gulfareen Akhtar, Hany Habashy, Tarek Abdel-Fatah, Emad A Rakha, Andrew R Green, Ian O Ellis Breast Cancer Research 2009, 11:R90 (21 December 2009)
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MTHFR C677T and postmenopausal breast cancer risk by intakes of one-carbon metabolism nutrients: a nested case-control study
Sonia S Maruti, Cornelia M Ulrich, Eldon R Jupe, Emily White Breast Cancer Research 2009, 11:R91 (23 December 2009)
Abstract | Full text | PDF | PubMed
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Editor’s summary
The common MTHFR C677T polymorphism is associated with a moderately increased risk of post-menopausal breast cancer, an effect that may be lessened by high dietary intake of one-carbon associated nutrients.
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