Breast Cancer Research

official impact factor 5.79

Open Access Research article

Comprehensive characterization of the DNA amplification at 13q34 in human breast cancer reveals TFDP1 and CUL4A as likely candidate target genes

Lorenzo Melchor1,6, Laura Paula Saucedo-Cuevas1, Iván Muñoz-Repeto1, Socorro María Rodríguez-Pinilla2, Emiliano Honrado1, Alfredo Campoverde3, Jose Palacios2, Katherine L Nathanson4, María José García1,5 and Javier Benítez1,5*

Author Affiliations

1 Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Center (CNIO), Madrid, E-28029, Spain

2 Breast and Gynecological Group, Molecular Pathology Program, Spanish National Cancer Research Center (CNIO), Madrid, E-28029, Spain

3 The Institute of Cancer SOLCA, Cuenca, Ecuador

4 Department of Medicine, Medical Genetics, Abramson Cancer Center, University of Pennsylvania (UPENN), Philadelphia, PA-19104, USA

5 Center for Biomedical Research on Rare Diseases (CIBERER), Calle de Alvaro de Bazan, 10 Bajo, 46010 Valencia, Spain

6 Current address: The Breakthrough Breast Cancer Research Center, The Institute of Cancer Research (ICR), SW3 6JB, UK

For all author emails, please log on.

Breast Cancer Research 2009, 11:R86 doi:10.1186/bcr2456

Published: 8 December 2009

Additional files

Additional file 1:

Word document containing a table showing genes, primers and Universal Probe Library from Roche© used for qRT-PCR analyses in the present study.

Format: DOC Size: 71KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional file 2:

Word file containing a table listing the antibodies used in the present immunohistochemical analysis and thresholds established to consider a tumor as positive.

Format: DOC Size: 60KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data