Figure 4.

Immunohistochemical staining for CUL4A (a-c) and TFDP1 (d-f) in tumors with and without Amp13q34. (a) Null CUL4A staining in a non-amplifier tumor sample. (b) Moderate CUL4A staining in a non-amplifier tumor sample. (c) Strong CUL4A staining in a tumor with the Amp13q34. (d) Negative TFDP1 expression in a tumor without Amp13q34. (e) and (f) Strong TFDP1 expression in tumors with Amp13q34, the arrow in (f) points out the absence of expression in a lymphocyte infiltrate compared with the breast tumor cells.