Table 2

Rates of breast cancer relapse and hazard ratios related to dose intensity of chemotherapy

Subset

Dose intensity of chemotherapy

No radiation (%)

Radiation (%)

Hazard ratio (DFS)

Arriagada and colleagues [20]

Node-negative

0.0

59

47

0.70

Node-positive

82

67

0.65

Overgaard and colleagues [2]

N1 to N3

0.4

53

37

0.61

N4⁺

76

60

0.64

Ragaz and colleagues [1]

N1 to N3

0.6

48

36

0.68

N4⁺

83

62

0.55

Absolute and relative rates of breast cancer relapse (%) and hazard ratios related to the dose intensity of chemotherapy. N1 to N3, one to three axillary nodes involved; (N4⁺), four or more axillary nodes involved. DFS, first event breast cancer recurrence (or any death).

Ragaz Breast Cancer Research 2009 11(Suppl 3):S14   doi:10.1186/bcr2433