Table 2

Rates of breast cancer relapse and hazard ratios related to dose intensity of chemotherapy

Subset
Dose intensity of chemotherapy
No radiation (%)
Radiation (%)
Hazard ratio (DFS)

Arriagada and colleagues [20]
     Node-negative
0.0
59
47
0.70
     Node-positive

82
67
0.65
Overgaard and colleagues [2]
     N1 to N3
0.4
53
37
0.61
     N4+

76
60
0.64
Ragaz and colleagues [1]
     N1 to N3
0.6
48
36
0.68
     N4+

83
62
0.55

Absolute and relative rates of breast cancer relapse (%) and hazard ratios related to the dose intensity of chemotherapy. N1 to N3, one to three axillary nodes involved; (N4+), four or more axillary nodes involved. DFS, first event breast cancer recurrence (or any death).

Ragaz Breast Cancer Research 2009 11(Suppl 3):S14   doi:10.1186/bcr2433