Breast Cancer Research

official impact factor 5.79

Open Access Highly Access Research article

Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies

Rituparna Mukhopadhyay1, Sylvain V Costes1, Alexey V Bazarov2, William C Hines1, Mary H Barcellos-Hoff1,3 and Paul Yaswen1*

Author Affiliations

1 Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 USA

2 Department of Laboratory Medicine, University of California, San Francisco, CA 94143 USA

3 Department of Radiation Oncology, New York University School of Medicine, New York, NY 10016 USA

For all author emails, please log on.

Breast Cancer Research 2010, 12:R11 doi:10.1186/bcr2477

Published: 10 February 2010

Additional files

Additional file 1:

Supplementary Figure S1 - X-irradiation does not induce p16 directly. p16 immunohistochemistry indicates that 3p HMEC cultures derived from specimen N17 did not express detectable p16 protein 24 hrs after irradiation with 2 Gy X-rays. Indicated negative and positive controls for specific antibody-dependent staining are shown in left panels.

Format: PDF Size: 85KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data