Table 4 |
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|
Age-adjusted incidence rate (AAIR) of invasive and in situ breast cancer according to hormone therapy (HT) use at follow-up in 2000-2001 among menopausal women in the California Teachers Study |
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|
Period |
Never HT |
Past HT |
Current E |
Current EP |
|
|
||||
|
AAIR (95% CI) |
AAIR (95% CI) |
AAIR (95% CI) |
AAIR (95% CI) |
|
|
|
||||
|
Invasive breast cancer |
||||
|
2001-02 |
369.3 (285.6-452.9) |
561.1 (432.4-689.8) |
534.9 (424.7-645.1) |
665.8 (565.9-765.7) |
|
2003-05 |
343.7 (272.8-414.5) |
340.0 (265.6-414.4) |
406.4 (324.7-488.0) |
461.9 (392.5-531.4) |
|
|
||||
|
% change |
-6.9% P = 0.33 |
-39.4% P = 0.003 |
-24.0% P = 0.030 |
-30.6% P = 0.001 |
|
|
||||
|
In Situ breast cancer |
||||
|
2001-02 |
86.6 (44.0-129.1) |
100.5 (32.4-168.6) |
137.7 (83.2-192.3) |
135.0 (95.2-174.9) |
|
2003-05 |
107.2 (63.1-151.3) |
99.5 (60.3-138.8) |
123.6 (67.3-179.9) |
115.5 (78.1-152.8) |
|
|
||||
|
% change |
23.8% P = 0.26 |
-1.0% P = 0.49 |
-10.2% P = 0.35 |
-14.4% P = 0.22 |
|
|
||||
|
CI = confidence interval; E = estrogen only; EP = estrogen and progestin combined therapy. |
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|
Marshall et al. Breast Cancer Research 2010 12:R4 doi:10.1186/bcr2467 |
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