Table 1

Patient characteristics for model development (ECRIC) and validation (WMCIU) cohorts

ECRIC
WMCIU
Total Number of Subjects
 5,694
5,468
Total time at risk (years)
 31,904
25,917
Median follow-up (years)*
 5.65
 (0.04-8.00)†
 4.85
 (0.07-8.00)†
Number of breast cancer deaths
 737
668
Number of other deaths
 338
287
Annual breast cancer mortality rate
 0.023
 (0.021-0.025)‡
 0.026
 (0.024-0.028)‡
5-year breast cancer survival rate
 0.89
 (0.88-0.90)‡
 0.88
 (0.87-0.89)‡
Median age at diagnosis, years
 58
 (23-95)†
 58
 (22-93)†

Number
 %
 Number
 %
Age, years



     <35
 111
 2
 108
 2
     35-49
 1,172
 21
 1,195
 22
     50-64
 2,630
 46
 2,393
 44
     65-74
 1,124
 20
 1,101
 20
     75+
 657
 12
 671
 12
Nodal status



     0
 3,532
 62
 3,184
 58
     1
 741
 13
 746
 14
     2-4
 806
 14
 792
 14
     5-9
 380
 7
 451
 8
     10+
 235
 4
 295
 5
Tumour size, mm



     <10
 625
 11
 485
 9
     10-19
 2,310
 41
 2,136
 39
     20-29
 1,627
 29
 1,566
 29
     30-49
 845
 15
 923
 17
     50+
 287
 5
 358
 7
Grade



     I
 1,005
 18
 1,017
 19
     II
 2,927
 51
 2,442
 45
     III
 1,762
 31
 2,009
 37
ER Status



     ER negative
 991
 17
 1,116
 20
     ER positive
 4,703
 83
 4,352
 80
Adjuvant therapy



     None
 643
 11
 1,520
 28
     Chemotherapy only
 783
 14
 1,542
 28
     Endocrine therapy
 3,146
 55
 1,827
 33
     Combined chemoendocrine
 1,122
 20
 579
 11
Screen detected



     Yes
 1,621
 28
 1,256
 23
     No
 4,073
 72
 4,212
 77

*Follow-up censored at 8 years

†Range of variable

‡95 CI

Wishart et al. Breast Cancer Research 2010 12:401   doi:10.1186/bcr2480