Breast Cancer Research

official impact factor 5.79

Open Access Highly Access Research article

Prediction of breast cancer sensitivity to neoadjuvant chemotherapy based on status of DNA damage repair proteins

Hideki Asakawa1,2, Hirotaka Koizumi3, Ayaka Koike1,2, Makiko Takahashi3, Wenwen Wu1, Hirotaka Iwase4, Mamoru Fukuda1 and Tomohiko Ohta1,2*

Author Affiliations

1 Division of Breast and Endocrine Surgery, Department of Surgery, St. Marianna University School of Medicine, Kawasaki, 216-8511 Japan

2 Department of Translational Oncology, St. Marianna University Graduate School of Medicine, Kawasaki, 216-8511 Japan

3 Department of Diagnostic Pathology, St. Marianna University School of Medicine, Kawasaki, 216-8511 Japan

4 Department of Breast and Endocrine Surgery, Kumamoto University, Honjo 1-1-1, Kumamoto 860-8556, Japan

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Breast Cancer Research 2010, 12:R17 doi:10.1186/bcr2486

Published: 5 March 2010

Additional files

Additional file 1:

Table S1. Antibodies used in the present immunohistochemical study.

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Additional file 2:

Figure S1. Mean tumor volume reduction after EC (a) or EC+DOC (b) according to the nuclear foci status for DNA repair proteins.

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Additional file 3:

Table S2. Tumor response rate according to the nuclear foci status for DNA repair proteins.

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