Table 5 |
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|
Expression of HSP90, PI3K-p110α, and PTEN loss according to intrinsic subtypes |
|||||||||
|
Luminal A (n = 131) |
Luminal B (n = 18) |
Triple negative (n = 37) |
HER2+/ER- (n = 26) |
P value |
|||||
|
|
|
|
|
||||||
|
n |
(%) |
n |
(%) |
n |
(%) |
n |
(%) |
||
|
|
|||||||||
|
HSP90 |
86 |
(66) |
13 |
(72) |
18 |
(49) |
17 |
(65) |
0.208 |
|
PI3K-p110α |
79 |
(62) |
13 |
(72) |
25 |
(68) |
21 |
(81) |
0.296 |
|
PTEN loss |
29 |
(22) |
6 |
(33) |
17 |
(46) |
5 |
(19) |
0.023 |
|
|
|||||||||
|
HSP90 = heat-shock protein 90; PI3K = phosphatidylinositol-3-kinase; PTEN = phosphatase and tensin homologue deleted on chromosome 10. |
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|
Song et al. Breast Cancer Research 2010 12:R20 doi:10.1186/bcr2557 |
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