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Volume 12 Issue 3
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Comment |
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At last, a predictive and prognostic marker for radiotherapy?
Philip Coates, John Dewar, Alastair M Thompson Breast Cancer Research 2010, 12:106 (11 May 2010)
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Breast tumors: of mice and women
Sean P McDermott, Max S Wicha Breast Cancer Research 2010, 12:108 (27 May 2010)
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What do we learn from HER2-positive breast cancer genomic profiles?
Charles Theillet Breast Cancer Research 2010, 12:107 (1 June 2010)
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Just when you thought it was safe to go into the membrane: the growing complexities of extra-nuclear progesterone signaling
Aritro Sen, Stephen R Hammes Breast Cancer Research 2010, 12:109 (16 June 2010)
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Managing bone mineral density with oral bisphosphonate therapy in women with breast cancer receiving adjuvant aromatase inhibition
Catherine Van Poznak Breast Cancer Research 2010, 12:110 (18 June 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Review |
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Tumour-associated carbohydrate antigens in breast cancer
Aurélie Cazet, Sylvain Julien, Marie Bobowski, Joy Burchell, Philippe Delannoy Breast Cancer Research 2010, 12:204 (8 June 2010)
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The contribution of dynamic stromal remodeling during mammary development to breast carcinogenesis
Jessica McCready, Lisa M Arendt, Jenny A Rudnick, Charlotte Kuperwasser Breast Cancer Research 2010, 12:205 (17 June 2010)
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Key signalling nodes in mammary gland development and cancer. The Snail1-Twist1 conspiracy in malignant breast cancer progression
Ellen Foubert, Bram De Craene, Geert Berx Breast Cancer Research 2010, 12:206 (25 June 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Research |
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High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer
Johan Staaf, Göran Jönsson, Markus Ringnér, Johan Vallon-Christersson, Dorthe Grabau, Adalgeir Arason, Haukur Gunnarsson, Bjarni A Agnarsson, Per-Olof Malmström, Oskar Johannsson, Niklas Loman, Rosa B Barkardottir, Åke Borg Breast Cancer Research 2010, 12:R25 (6 May 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
A survey of copy number alterations in HER2+ breast tumors using a combination of array comparative genomic hybridization and gene expression analyses pinpoints significant genomic aberrations, including potentially novel therapeutic targets.
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Cyclophosphamide- metabolizing enzyme polymorphisms and survival outcomes after adjuvant chemotherapy for node-positive breast cancer: a retrospective cohort study
Priya P Gor, H Irene Su, Robert J Gray, Phyllis A Gimotty, Michelle Horn, Richard Aplenc, William P Vaughan, Martin S Tallman, Timothy R Rebbeck, Angela DeMichele Breast Cancer Research 2010, 12:R26 (10 May 2010)
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Inhibition of phosphatidylcholine-specific phospholipase C downregulates HER2 overexpression on plasma membrane of breast cancer cells
Luisa Paris, Serena Cecchetti, Francesca Spadaro, Laura Abalsamo, Luana Lugini, Maria Elena Pisanu, Egidio Iorio, Pier Giorgio Natali, Carlo Ramoni, Franca Podo Breast Cancer Research 2010, 12:R27 (12 May 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Incorporating tumour pathology information into breast cancer risk prediction algorithms
Nasim Mavaddat, Timothy R Rebbeck, Sunil R Lakhani, Douglas F Easton, Antonis C Antoniou Breast Cancer Research 2010, 12:R28 (18 May 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Including tumour pathology information in breast cancer prediction models influences the predicted probabilities of carrying a BRCA1 or BRCA2 mutation and may have implications for genetic testing and clinical decision making.
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Novel design principles enable specific targeting of imaging and therapeutic agents to necrotic domains in breast tumors
Liat Goldshaid, Efrat Rubinstein, Alexander Brandis, Dadi Segal, Noa Leshem, Ori Brenner, Vyacheslav Kalchenko, Doron Eren, Tamar Yecheskel, Yoseph Salitra, Yoram Salomon, Avigdor Scherz Breast Cancer Research 2010, 12:R29 (24 May 2010)
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Breast cancer-specific mutations in CK1ε inhibit Wnt/β-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration
Silvie Foldynová-Trantírková, Petra Sekyrová, Kateřina Tmejová, Eva Brumovská, Ondřej Bernatík, Wulf Blankenfeldt, Pavel Krejčí, Alois Kozubík, Tomáš Doležal, Lukáš Trantírek, Vítězslav Bryja Breast Cancer Research 2010, 12:R30 (27 May 2010)
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Senescence evasion by MCF-7 human breast tumor-initiating cells
Feridoun Karimi-Busheri, Aghdass Rasouli-Nia, John R Mackey, Michael Weinfeld Breast Cancer Research 2010, 12:R31 (2 June 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Understanding the inherent down-regulation of senescence pathways that offer breast cancer tumour-initiating cells protection against ionising radiation may help characterise the cellular pathways used by cancer stem cells to enhance survival.
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Anterior gradient-2 plays a critical role in breast cancer cell growth and survival by modulating cyclin D1, estrogen receptor-α and survivin
Kathryn E Vanderlaag, Susan Hudak, Laura Bald, Laurence Fayadat-Dilman, Manjiri Sathe, Jeff Grein, Mary J Janatpour Breast Cancer Research 2010, 12:R32 (4 June 2010)
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Prospectively measured triiodothyronine levels are positively associated with breast cancer risk in postmenopausal women
Ada Tosovic, Anne-Greth Bondeson, Lennart Bondeson, Ulla-Britt Ericsson, Johan Malm, Jonas Manjer Breast Cancer Research 2010, 12:R33 (11 June 2010)
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Progesterone reverses the mesenchymal phenotypes of basal phenotype breast cancer cells via a membrane progesterone receptor mediated pathway
Lian Zuo, Wei Li, Shaojin You Breast Cancer Research 2010, 12:R34 (11 June 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Pregnancy-related factors and the risk of breast carcinoma in situ and invasive breast cancer among postmenopausal women in the California Teachers Study cohort
Huiyan Ma, Katherine D Henderson, Jane Sullivan-Halley, Lei Duan, Sarah F Marshall, Giske Ursin, Pamela L Horn-Ross, Joan Largent, Dennis M Deapen, James V Lacey, Leslie Bernstein Breast Cancer Research 2010, 12:R35 (18 June 2010)
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Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns
Karolina Holm, Cecilia Hegardt, Johan Staaf, Johan Vallon-Christersson, Göran Jönsson, Håkan Olsson, Åke Borg, Markus Ringnér Breast Cancer Research 2010, 12:R36 (18 June 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Breast cancers of the basal-like, luminal A and luminal B molecular subtypes harbour specific methylation profiles, suggesting that methylation may play an important role in the development of breast cancers.
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The role of chemotherapeutic drugs in the evaluation of breast tumour response to chemotherapy using serial FDG-PET
Michal E Schneider-Kolsky, Stewart Hart, Jane Fox, Peter Midolo, John Stuckey, Michael Hofman, Vinod Ganju Breast Cancer Research 2010, 12:R37 (21 June 2010)
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Cooperative signaling between Wnt1 and integrin-linked kinase induces accelerated breast tumor development
Arusha Oloumi, Mykola Maidan, Frances E Lock, Howard Tearle, Steven McKinney, William J Muller, Samuel AJR Aparicio, Shoukat Dedhar Breast Cancer Research 2010, 12:R38 (21 June 2010)
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Dynamic changes in gene expression in vivo predict prognosis of tamoxifen-treated patients with breast cancer
Karen J Taylor, Andrew H Sims, Liang Liang, Dana Faratian, Morwenna Muir, Graeme Walker, Barbara Kuske, J Michael Dixon, David A Cameron, David J Harrison, Simon P Langdon Breast Cancer Research 2010, 12:R39 (22 June 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer
Chad J Creighton, Xiaoyong Fu, Bryan T Hennessy, Angelo J Casa, Yiqun Zhang, Ana Maria Gonzalez-Angulo, Ana Lluch, Joe W Gray, Powell H Brown, Susan G Hilsenbeck, C Kent Osborne, Gordon B Mills, Adrian V Lee, Rachel Schiff Breast Cancer Research 2010, 12:R40 (22 June 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells
Joshua A Bauer, Fei Ye, Clayton B Marshall, Brian D Lehmann, Christopher S Pendleton, Yu Shyr, Carlos L Arteaga, Jennifer A Pietenpol Breast Cancer Research 2010, 12:R41 (24 June 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics
Göran Jönsson, Johan Staaf, Johan Vallon-Christersson, Markus Ringnér, Karolina Holm, Cecilia Hegardt, Haukur Gunnarsson, Rainer Fagerholm, Carina Strand, Bjarni A Agnarsson, Outi Kilpivaara, Lena Luts, Päivi Heikkilä, Kristiina Aittomäki, Carl Blomqvist, Niklas Loman, Per Malmström, Håkan Olsson, Oskar Th Johannsson, Adalgeir Arason, Heli Nevanlinna, Rosa B Barkardottir, Åke Borg Breast Cancer Research 2010, 12:R42 (24 June 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
The identification of six subtypes of breast cancer - differing in biology, genomic alterations and patient outcome - may prove useful for understanding tumor development and for prognostic and treatment prediction purposes.
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The estrogen receptor influences microtubule-associated protein tau (MAPT) expression and the selective estrogen receptor inhibitor fulvestrant downregulates MAPT and increases the sensitivity to taxane in breast cancer cells
Hirokuni Ikeda, Naruto Taira, Fumikata Hara, Takeo Fujita, Hiromasa Yamamoto, Junichi Soh, Shinichi Toyooka, Tomohiro Nogami, Tadahiko Shien, Hiroyoshi Doihara, Shinichiro Miyoshi Breast Cancer Research 2010, 12:R43 (28 June 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Role of thioredoxin reductase 1 and thioredoxin interacting protein in prognosis of breast cancer
Cristina Cadenas, Dennis Franckenstein, Marcus Schmidt, Mathias Gehrmann, Matthias Hermes, Bettina Geppert, Wiebke Schormann, Lindsey J Maccoux, Markus Schug, Anika Schumann, Christian Wilhelm, Evgenia Freis, Katja Ickstadt, Jörg Rahnenführer, Jörg I Baumbach, Albert Sickmann, Jan G Hengstler Breast Cancer Research 2010, 12:R44 (28 June 2010)
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Correspondence |
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Association between the spread of circulating tumor cells and breast cancer subtypes
Xiaowei Qi, Xinhua Yang, Linjun Fan, Yi Zhang, Fan Zhang, Jun Jiang Breast Cancer Research 2010, 12:402 (17 June 2010)
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