Table 3 |
|||||
|
Correlation between HOXB13 protein levels and prognostic factors analyzed with the chi-square test for trend |
|||||
|
HOXB13 expression |
P value |
||||
|
|
|||||
|
Negative |
Low |
Intermediate |
High |
||
|
|
|||||
|
Tumor size |
|||||
|
≤20 mm |
205 (31.0) |
249 (37.7) |
168 (25.4) |
39 (5.9) |
|
|
>20 mm |
78 (43.1) |
59 (32.6) |
37 (20.4) |
7 (3.9 |
0.0048 |
|
Human epidermal growth factor receptor 2 |
|||||
|
0 |
189 (38.4) |
172 (35.0) |
102 (20.7) |
29 (5.9) |
|
|
1+ |
38 (26.6) |
55 (38.5) |
45 (31.5) |
5 (3.5) |
|
|
2+ |
16 (20.5) |
32 (41.0) |
26 (33.3) |
4 (5.1) |
|
|
3+ |
27 (29.7) |
30 (33.0) |
27 (29.7) |
7 (7.7) |
0.0023 |
|
Estrogen receptor* |
|||||
|
0 |
63 (39.4) |
48 (30.0) |
34 (21.3) |
15 (9.4) |
|
|
1 to 24 |
5 (35.7) |
5 (35.7) |
4 (28.6) |
0 (0) |
|
|
25 to 74 |
69 (57.0) |
35 (28.9) |
16 (13.2) |
1 (0.8) |
|
|
75 to 89 |
63 (33.3) |
67 (35.5) |
47 (24.9) |
12 (6.4) |
|
|
>90 |
62 (22.1) |
110 (39.3) |
96 (34.3) |
12 (4.3) |
0.0022 |
|
Progesterone receptor* |
|||||
|
0 |
120 (39.9) |
92 (30.6) |
68 (22.6) |
21 (7.0) |
|
|
1 to 24 |
43 (42.6) |
29 (28.7) |
26 (25.7) |
3 (3.0) |
|
|
25 to 74 |
58 (29.3) |
87 (43.9) |
48 (24.2) |
5 (2.5) |
|
|
75 to 89 |
27 (24.1) |
42 (37.5) |
33 (29.5) |
10 (8.9) |
|
|
>90 |
20 (36.4) |
21 (38.2) |
12 (21.8) |
2 (3.6) |
0.13 |
|
|
|||||
|
Data presented as number of patients (%).*Percentage of positive nuclei stained with immunohistochemistry. |
|||||
|
Jerevall et al. Breast Cancer Research 2010 12:R53 doi:10.1186/bcr2612 |
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