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Volume 13 Issue 1
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Comment |
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Chasing the immortal strand: evidence for nature's way of protecting the breast genome
Nikolajs Zeps, Christine Hemmings Breast Cancer Research 2011, 13:101 (17 January 2011)
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Appraisal of progenitor markers in the context of molecular classification of breast cancers
Izhak Haviv Breast Cancer Research 2011, 13:102 (25 January 2011)
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3D culture reveals a signaling network
Senthil K Muthuswamy Breast Cancer Research 2011, 13:103 (27 January 2011)
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Breast cancer genome heterogeneity: a challenge to personalised medicine?
Charles Swanton, Rebecca A Burrell, P Andrew Futreal Breast Cancer Research 2011, 13:104 (1 February 2011)
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A local basis for progesterone action during mammary tumorigenesis - no longer RANK and file
Whitney K Petrie, Russell C Hovey Breast Cancer Research 2011, 13:301 (28 January 2011)
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High hopes for RANKL: will the mouse model live up to its promise?
Tamara Tanos, Cathrin Brisken Breast Cancer Research 2011, 13:302 (28 January 2011)
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Review |
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Gene signatures of breast cancer progression and metastasis
David I Rodenhiser, Joseph D Andrews, Theodore A Vandenberg, Ann F Chambers Breast Cancer Research 2011, 13:201 (24 January 2011)
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Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression
Caitlin D May, Nathalie Sphyris, Kurt W Evans, Steven J Werden, Wenjun Guo, Sendurai A Mani Breast Cancer Research 2011, 13:202 (8 February 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Functional magnetic resonance: biomarkers of response in breast cancer
Elizabeth AM O'Flynn, Nandita M deSouza Breast Cancer Research 2011, 13:204 (23 February 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central |
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Do aromatase inhibitors have adverse effects on cognitive function?
Kelly Phillips, Karin Ribi, Richard Fisher Breast Cancer Research 2011, 13:203 (23 February 2011)
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Research |
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α-TEA cooperates with chemotherapeutic agents to induce apoptosis of p53 mutant, triple-negative human breast cancer cells via activating p73
Richa Tiwary, Weiping Yu, Bob G Sanders, Kimberly Kline Breast Cancer Research 2011, 13:R1 (7 January 2011)
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Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth
Li Xu Yan, Qi Nian Wu, Yan Zhang, Yang Yang Li, Ding Zhun Liao, Jing Hui Hou, Jia Fu, Mu Sheng Zeng, Jing Ping Yun, Qiu Liang Wu, Yi Xin Zeng, Jian Yong Shao Breast Cancer Research 2011, 13:R2 (10 January 2011)
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A p53-independent role of Mdm2 in estrogen-mediated activation of breast cancer cell proliferation
Angelika Brekman, Kathryn E Singh, Alla Polotskaia, Nandini Kundu, Jill Bargonetti Breast Cancer Research 2011, 13:R3 (11 January 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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α-Tocopheryloxyacetic acid: a novel chemotherapeutic that stimulates the antitumor immune response
Tobias Hahn, Bhumasamudram Jagadish, Eugene A Mash, Kendra Garrison, Emmanuel T Akporiaye Breast Cancer Research 2011, 13:R4 (13 January 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Proliferation-associated POU4F2/Brn-3b transcription factor expression is regulated by oestrogen through ERα and growth factors via MAPK pathway
Samir Ounzain, Samantha Bowen, Chandrakant Patel, Rieko Fujita, Richard J Heads, Vishwanie S Budhram-Mahadeo Breast Cancer Research 2011, 13:R5 (17 January 2011)
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Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: results from a breast cancer family registry case-control mutation-screening study
Florence Le Calvez-Kelm, Fabienne Lesueur, Francesca Damiola, Maxime Vallée, Catherine Voegele, Davit Babikyan, Geoffroy Durand, Nathalie Forey, Sandrine McKay-Chopin, Nivonirina Robinot, Tù Nguyen-Dumont, Alun Thomas, Graham B Byrnes, Breast Cancer Family Registry, John L Hopper, Melissa C Southey, Irene L Andrulis, Esther M John, Sean V Tavtigian Breast Cancer Research 2011, 13:R6 (18 January 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients
Jean-Christophe Bourdon, Marie P Khoury, Alexandra Diot, Lee Baker, Kenneth Fernandes, Mustapha Aoubala, Philip Quinlan, Colin A Purdie, Lee B Jordan, Anne-Catherine Prats, David P Lane, Alastair M Thompson Breast Cancer Research 2011, 13:R7 (20 January 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Association of functional polymorphisms in CYP19A1 with aromatase inhibitor associated arthralgia in breast cancer survivors
Jun J Mao, H Irene Su, Rui Feng, Michelle L Donelson, Richard Aplenc, Timothy R Rebbeck, Frank Stanczyk, Angela DeMichele Breast Cancer Research 2011, 13:R8 (20 January 2011)
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Enhanced RAD21 cohesin expression confers poor prognosis and resistance to chemotherapy in high grade luminal, basal and HER2 breast cancers
Huiling Xu, Max Yan, Jennifer Patra, Rachael Natrajan, Yuqian Yan, Sigrid Swagemakers, Jonathan M Tomaszewski, Sandra Verschoor, Ewan KA Millar, Peter van der Spek, Jorge S Reis-Filho, Robert G Ramsay, Sandra A O'Toole, Catriona M McNeil, Robert L Sutherland, Michael J McKay, Stephen B Fox Breast Cancer Research 2011, 13:R9 (21 January 2011)
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Genetic variation of ESR1 and its co-activator PPARGC1B is synergistic in augmenting the risk of estrogen receptor-positive breast cancer
Yuqing Li, Yi Li, Sara Wedrén, Guoliang Li, Tze Howe Charn, Kartiki Vasant Desai, Carine Bonnard, Kamila Czene, Keith Humphreys, Hatef Darabi, Kristjana Einarsdóttir, Tuomas Heikkinen, Kristiina Aittomäki, Carl Blomqvist, Kee Seng Chia, Heli Nevanlinna, Per Hall, Edison T Liu, Jianjun Liu Breast Cancer Research 2011, 13:R10 (26 January 2011)
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Prolactin-induced mouse mammary carcinomas model estrogen resistant luminal breast cancer
Lisa M Arendt, Debra E Rugowski, Tara A Grafwallner-Huseth, Maria Jose Garcia-Barchino, Hallgeir Rui, Linda A Schuler Breast Cancer Research 2011, 13:R11 (28 January 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifen
Donal J Brennan, Henriette Laursen, Darran P O'Connor, Signe Borgquist, Mathias Uhlen, William M Gallagher, Fredrik Pontén, Robert C Millikan, Lisa Rydén, Karin Jirström Breast Cancer Research 2011, 13:R12 (31 January 2011)
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Editor’s summary
Breast cancer patients treated with tamoxifen who had HMG-CoAR positive tumors had improved recurrence-free survival rates compared to those with HMG-CoAR negative tumors.
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Genetic variation in the genome-wide predicted estrogen response element-related sequences is associated with breast cancer development
Jyh-Cherng Yu, Chia-Ni Hsiung, Huan-Ming Hsu, Bo-Ying Bao, Shou-Tung Chen, Giu-Cheng Hsu, Wen-Cheng Chou, Ling-Yueh Hu, Shian-Ling Ding, Chun-Wen Cheng, Pei-Ei Wu, Chen-Yang Shen Breast Cancer Research 2011, 13:R13 (31 January 2011)
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Contribution of large genomic BRCA1 alterations to early-onset breast cancer selected for family history and tumour morphology: a report from The Breast Cancer Family Registry
Letitia D Smith, Andrea A Tesoriero, Ee M Wong, Susan J Ramus, Frances P O'Malley, Anna Marie Mulligan, Mary Beth Terry, Ruby T Senie, Regina M Santella, Esther M John, Irene L Andrulis, Hilmi Ozcelik, Mary B Daly, Andrew K Godwin, Saundra S Buys, Stephen Fox, David E Goldgar, Graham G Giles, John L Hopper, Melissa C Southey Breast Cancer Research 2011, 13:R14 (31 January 2011)
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Quantification and clinical relevance of gene amplification at chromosome 17q12-q21 in human epidermal growth factor receptor 2-amplified breast cancers
Pierre-Jean Lamy, Frédéric Fina, Caroline Bascoul-Mollevi, Anne-Claire Laberenne, Pierre-Marie Martin, L'Houcine Ouafik, William Jacot Breast Cancer Research 2011, 13:R15 (2 February 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
HER2 amplification seems to drive genomic instability along chromosome 17q leading to different patterns of gene amplification, and patients with hormone receptor-negative and non-amplified TOP2A cancers had the worst prognosis.
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The prolyl hydroxylase enzymes are positively associated with hypoxia-inducible factor-1α and vascular endothelial growth factor in human breast cancer and alter in response to primary systemic treatment with epirubicin and tamoxifen
Stephen B Fox, Daniele Generali, Alfredo Berruti, Maria P Brizzi, Leticia Campo, Simone Bonardi, Alessandra Bersiga, Giovanni Allevi, Manuela Milani, Sergio Aguggini, Teresa Mele, Luigi Dogliotti, Alberto Bottini, Adrian L Harris Breast Cancer Research 2011, 13:R16 (3 February 2011)
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Vaccination with human anti-trastuzumab anti-idiotype scFv reverses HER2 immunological tolerance and induces tumor immunity in MMTV.f.huHER2(Fo5) mice
Maha Z Ladjemi, Thierry Chardes, Stephanie Corgnac, Veronique Garambois, Sebastien Morisseau, Bruno Robert, Caroline Bascoul-Mollevi, Imade Ait Arsa, William Jacot, Jean-Pierre Pouget, Andre Pelegrin, Isabelle Navarro-Teulon Breast Cancer Research 2011, 13:R17 (4 February 2011)
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During hormone depletion or tamoxifen treatment of breast cancer cells the estrogen receptor apoprotein supports cell cycling through the retinoic acid receptor α1 apoprotein
Marcela D Salazar, Maya Ratnam, Mugdha Patki, Ivana Kisovic, Robert Trumbly, Mohamed Iman, Manohar Ratnam Breast Cancer Research 2011, 13:R18 (7 February 2011)
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The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression
Peter Chan, Andreas Möller, Mira CP Liu, Jaclyn E Sceneay, Christina SF Wong, Nic Waddell, Katie T Huang, Alexander Dobrovic, Ewan KA Millar, Sandra A O'Toole, Catriona M McNeil, Robert L Sutherland, David D Bowtell, Stephen B Fox Breast Cancer Research 2011, 13:R19 (9 February 2011)
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Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals
Kirsi M Kuusisto, Aleksandra Bebel, Mauno Vihinen, Johanna Schleutker, Satu-Leena Sallinen Breast Cancer Research 2011, 13:R20 (28 February 2011)
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Correspondence |
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Circulating fatty acid synthase: an exploratory biomarker to predict efficacy of the dual HER1/HER2 tyrosine kinase inhibitor lapatinib
Cristina Oliveras-Ferraros, Sílvia Cufí, Tamara Sauri-Nadal, Sonia Barco, Begoña Martin-Castillo, Alejandro Vazquez-Martin, Javier A Menendez Breast Cancer Research 2011, 13:401 (24 January 2011)
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Circulating microRNAs: promising breast cancer Biomarkers
Helen M Heneghan, Nicola Miller, Michael J Kerin Breast Cancer Research 2011, 13:402 (4 February 2011)
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Circulating microRNAs: promising breast cancer biomarkers - authors' response
Carina Roth, Brigitte Rack, Volkmar Müller, Wolfgang Janni, Klaus Pantel, Heidi Schwarzenbach Breast Cancer Research 2011, 13:403 (4 February 2011)
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Mutation screening of RAD51C in male breast cancer patients
Valentina Silvestri, Piera Rizzolo, Mario Falchetti, Ines Zanna, Giovanna Masala, Domenico Palli, Laura Ottini Breast Cancer Research 2011, 13:404 (8 February 2011)
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