Breast Cancer Research

official impact factor 5.79

Highly Access Letter

Circulating microRNAs: promising breast cancer Biomarkers

Helen M Heneghan, Nicola Miller* and Michael J Kerin

Author Affiliations

Department of Surgery, National University of Ireland, Galway, Clinical Science Institute, Costello Road, Galway, Ireland

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Breast Cancer Research 2011, 13:402 doi:10.1186/bcr2798


See related research article by Roth et al., http://breast-cancer-research.com/content/12/6/R90 and related letter by Roth et al., http://breast-cancer-research.com/content/13/1/403

Published: 4 February 2011

First paragraph (this article has no abstract)

We read with interest the recent article by Roth and colleagues [1] reporting the findings of altered tumorspecific microRNAs (miRNAs) in sera of breast cancer patients. This report further substantiates emerging data suggesting that blood-based miRNAs have immense potential as novel non-invasive cancer biomarkers. However, we have several concerns regarding the authors' study.