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Volume 13 Issue 2
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Comment |
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Stratifying triple-negative breast cancer: which definition(s) to use?
Barbara Adamo, Carey K Anders Breast Cancer Research 2011, 13:105 (1 April 2011)
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Nanomedicine: making controllable magnetic drug delivery possible for the treatment of breast cancer
Lesa A Tran, Lon J Wilson Breast Cancer Research 2011, 13:303 (15 March 2011)
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ERBB receptors in cancer: signaling from the inside
Carlos L Arteaga Breast Cancer Research 2011, 13:304 (16 March 2011)
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Cell fate takes a slug in BRCA1-associated breast cancer
Geoffrey J Lindeman, Jane E Visvader Breast Cancer Research 2011, 13:306 (6 April 2011)
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More on FOX News: FOXA1 on the horizon of estrogen receptor function and endocrine response
Xiaoyong Fu, Catherine Huang, Rachel Schiff Breast Cancer Research 2011, 13:307 (20 April 2011)
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Review |
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Aromatase inhibitor-associated bone and musculoskeletal effects: new evidence defining etiology and strategies for management
Stéphanie Gaillard, Vered Stearns Breast Cancer Research 2011, 13:205 (14 March 2011)
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Signaling pathways in breast cancer metastasis - novel insights from functional genomics
Mario Blanco, Yibin Kang Breast Cancer Research 2011, 13:206 (14 March 2011)
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Therapeutic targets for bone metastases in breast cancer
Philippe Clézardin Breast Cancer Research 2011, 13:207 (6 April 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Stress and breast cancer: from epidemiology to molecular biology
Lilia Antonova, Kristan Aronson, Christopher R Mueller Breast Cancer Research 2011, 13:208 (21 April 2011)
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Research |
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Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer
Cesar G Sanchez, Cynthia X Ma, Robert J Crowder, Therese Guintoli, Chanpheng Phommaly, Feng Gao, Li Lin, Matthew J Ellis Breast Cancer Research 2011, 13:R21 (1 March 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Ki-67 can be used for further classification of triple negative breast cancer into two subtypes with different response and prognosis
Bhumsuk Keam, Seock-Ah Im, Kyung-Hun Lee, Sae-Won Han, Do-Youn Oh, Jee Kim, Se-Hoon Lee, Wonshik Han, Dong-Wan Kim, Tae-You Kim, In Park, Dong-Young Noh, Dae Heo, Yung-Jue Bang Breast Cancer Research 2011, 13:R22 (2 March 2011)
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Alternative TFAP2A isoforms have distinct activities in breast cancer
Chiara Berlato, KaYi V Chan, Anna M Price, Monica Canosa, Angelo G Scibetta, Helen C Hurst Breast Cancer Research 2011, 13:R23 (4 March 2011)
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Expression of microRNA and their gene targets are dysregulated in preinvasive breast cancer
Bethany N Hannafon, Paola Sebastiani, Antonio de las Morenas, Jining Lu, Carol L Rosenberg Breast Cancer Research 2011, 13:R24 (4 March 2011)
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Editor’s summary
Evidence altered miRNA expression can modulate gene expression, and miRNA expression profiles of normal breast epithelium and pre-invasive breast carcinoma, suggests miRNA dysregulation may be important in early breast cancer development
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Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis
Ola Blixt, Deanna Bueti, Brian Burford, Diane Allen, Sylvain Julien, Michael Hollingsworth, Alex Gammerman, Ian Fentiman, Joyce Taylor-Papadimitriou, Joy M Burchell Breast Cancer Research 2011, 13:R25 (8 March 2011)
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Pro-oncogene Pokemon promotes breast cancer progression by upregulating survivin expression
Xuyu Zu, Jun Ma, Hongxia Liu, Feng Liu, Chunyan Tan, Lingling Yu, Jue Wang, Zhenhua Xie, Deliang Cao, Yuyang Jiang Breast Cancer Research 2011, 13:R26 (10 March 2011)
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Estrogen receptor-beta sensitizes breast cancer cells to the anti-estrogenic actions of endoxifen
Xianglin Wu, Malayannan Subramaniam, Sarah B Grygo, Zhifu Sun, Vivian Negron, Wilma L Lingle, Matthew P Goetz, James N Ingle, Thomas C Spelsberg, John R Hawse Breast Cancer Research 2011, 13:R27 (10 March 2011)
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Impact of oncogenic K-RAS on YB-1 phosphorylation induced by ionizing radiation
Mahmoud Toulany, Tim-Andre Schickfluß, Wolfgang Eicheler, Rainer Kehlbach, Birgit Schittek, H Peter Rodemann Breast Cancer Research 2011, 13:R28 (10 March 2011)
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Fulvestrant-induced expression of ErbB3 and ErbB4 receptors sensitizes oestrogen receptor-positive breast cancer cells to heregulin β1
Iain R Hutcheson, Lindy Goddard, Denise Barrow, Richard A McClelland, Hayley E Francies, Janice M Knowlden, Robert I Nicholson, Julia MW Gee Breast Cancer Research 2011, 13:R29 (11 March 2011)
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Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice
Laura N Burga, Hai Hu, Ashish Juvekar, Nadine M Tung, Susan L Troyan, Erin W Hofstatter, Gerburg M Wulf Breast Cancer Research 2011, 13:R30 (11 March 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Breast cancer cell migration is regulated through junctional adhesion molecule-A-mediated activation of Rap1 GTPase
Elaine A McSherry, Kieran Brennan, Lance Hudson, Arnold DK Hill, Ann M Hopkins Breast Cancer Research 2011, 13:R31 (23 March 2011)
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Editor’s summary
Over-expression of junctional adhesion molecule–A (JAM-A) may be a new therapeutic target in breast cancer, as JAM-A signalling via activation of Rap1 GTPase and β1-integrin may facilitate metastatic spread.
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Estrogen receptor beta inhibits transcriptional activity of hypoxia inducible factor-1 through the downregulation of arylhydrocarbon receptor nuclear translocator
Wonchung Lim, Yeomyung Park, Jungyoon Cho, Choa Park, Joonwoo Park, Young-Kwon Park, Hyunsung Park, YoungJoo Lee Breast Cancer Research 2011, 13:R32 (24 March 2011)
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The indole-3-carbinol cyclic tetrameric derivative CTet inhibits cell proliferation via overexpression of p21/CDKN1A in both estrogen receptor-positive and triple-negative breast cancer cell lines
Mauro De Santi, Luca Galluzzi, Simone Lucarini, Maria Filomena Paoletti, Alessandra Fraternale, Andrea Duranti, Cinzia De Marco, Mirco Fanelli, Nadia Zaffaroni, Giorgio Brandi, Mauro Magnani Breast Cancer Research 2011, 13:R33 (24 March 2011)
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Adipokines, insulin resistance, metabolic syndrome, and breast cancer recurrence: a cohort study
Sang Oh, Cheol-Young Park, Eun Lee, Yeong Yoon, Eon Lee, Sang Park, Yuil Kim, Nak Sung, Young Yun, Keun Lee, Han Kang, Youngmee Kwon, Jungsil Ro Breast Cancer Research 2011, 13:R34 (30 March 2011)
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Mutations in the epidermal growth factor receptor (EGFR) gene in triple negative breast cancer: possible implications for targeted therapy
Yvonne Hui-Fang Teng, Wai-Jin Tan, Aye-Aye Thike, Poh-Yian Cheok, Gary Man-Kit Tse, Nan-Soon Wong, George Wai-Cheong Yip, Boon-Huat Bay, Puay-Hoon Tan Breast Cancer Research 2011, 13:R35 (1 April 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Synergy between inhibitors of androgen receptor and MEK has therapeutic implications in estrogen receptor-negative breast cancer
Ali Naderi, Kee Ming Chia, Ji Liu Breast Cancer Research 2011, 13:R36 (1 April 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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The association of polymorphisms in hormone metabolism pathway genes, menopausal hormone therapy, and breast cancer risk: a nested case-control study in the California Teachers Study cohort
Eunjung Lee, Fredrick Schumacher, Juan Pablo Lewinger, Susan L Neuhausen, Hoda Anton-Culver, Pamela L Horn-Ross, Katherine D Henderson, Argyrios Ziogas, David Van Den Berg, Leslie Bernstein, Giske Ursin Breast Cancer Research 2011, 13:R37 (1 April 2011)
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Editor’s summary
Polymorphisms of a solute carrier organic anion transporter gene, SLCO1B1, are associated with breast cancer risk in postmenopausal women, particularly among combined estrogen-progestin therapy users.
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Second malignancies in breast cancer patients following radiotherapy: a study in Florence, Italy
Wei Zhang, Aldo Becciolini, Annibale Biggeri, Paolo Pacini, Colin R Muirhead Breast Cancer Research 2011, 13:R38 (4 April 2011)
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miR-24-2 controls H2AFX expression regardless of gene copy number alteration and induces apoptosis by targeting antiapoptotic gene BCL-2: a potential for therapeutic intervention
Niloo Srivastava, Siddharth Manvati, Archita Srivastava, Ranjana Pal, Ponnusamy Kalaiarasan, Shilpi Chattopadhyay, Sailesh Gochhait, Raina Dua, Rameshwar NK Bamezai Breast Cancer Research 2011, 13:R39 (4 April 2011)
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Exploring the link between MORF4L1 and risk of breast cancer
Griselda Martrat, Christopher A Maxwell, Emiko Tominaga, Montserrat Porta-de-la-Riva, Núria Bonifaci, Laia Gómez-Baldó, Massimo Bogliolo, Conxi Lázaro, Ignacio Blanco, Joan Brunet, Helena Aguilar, Juana Fernández-Rodríguez, Sheila Seal, Anthony Renwick, Nazneen Rahman, Julia Kühl, Kornelia Neveling, Detlev Schindler, María J Ramírez, María Castellà, Gonzalo Hernández, EMBRACE, Douglas F Easton, Susan Peock, Margaret Cook, Clare T Oliver, Debra Frost, Radka Platte, D Gareth Evans, Fiona Lalloo et al.
Breast Cancer Research 2011, 13:R40 (5 April 2011)
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Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potential
Frances S Kittrell, Martha Z Carletti, Sofia Kerbawy, Jessica Heestand, Wa Xian, Mei Zhang, Heather L LaMarca, Arnoud Sonnenberg, Jeffrey M Rosen, Daniel Medina, Fariba Behbod Breast Cancer Research 2011, 13:R41 (5 April 2011)
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Genetic variation in PRL and PRLR, and relationships with serum prolactin levels and breast cancer risk: results from a population-based case-control study in Poland
Sarah J Nyante, Jessica M Faupel-Badger, Mark E Sherman, Ruth M Pfeiffer, Mia M Gaudet, Roni T Falk, Abegail A Andaya, Jolanta Lissowska, Louise A Brinton, Beata Peplonska, Barbara K Vonderhaar, Stephen Chanock, Montserrat Garcia-Closas, Jonine D Figueroa Breast Cancer Research 2011, 13:R42 (6 April 2011)
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Estrogen receptor β represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity
Karolina Lindberg, Luisa A Helguero, Yoko Omoto, Jan-Åke Gustafsson, Lars-Arne Haldosén Breast Cancer Research 2011, 13:R43 (14 April 2011)
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Quantitative assays for the measurement of HER1-HER2 heterodimerization and phosphorylation in cell lines and breast tumors: applications for diagnostics and targeted drug mechanism of action
Lisa DeFazio-Eli, Kristi Strommen, Trang Dao-Pick, Gordon Parry, Laurie Goodman, John Winslow Breast Cancer Research 2011, 13:R44 (15 April 2011)
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Targets of miR-200c mediate suppression of cell motility and anoikis resistance
Erin N Howe, Dawn R Cochrane, Jennifer K Richer Breast Cancer Research 2011, 13:R45 (18 April 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Micro RNA (miR) 200c reduces migration and invasion of carcinoma cells, and represses anoikis resistance through targeting a number of mesenchymal and neuronal genes.
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Trastuzumab-DM1 causes tumour growth inhibition by mitotic catastrophe in trastuzumab-resistant breast cancer cells in vivo
Mark Barok, Minna Tanner, Katri Köninki, Jorma Isola Breast Cancer Research 2011, 13:R46 (21 April 2011)
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Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers
Max Yan, Nicholas Jene, David Byrne, Ewan KA Millar, Sandra A O'Toole, Catriona M McNeil, Gaynor J Bates, Adrian L Harris, Alison H Banham, Robert L Sutherland, Stephen B Fox Breast Cancer Research 2011, 13:R47 (26 April 2011)
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