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Volume 13 Issue 6
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Comment |
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Breast cancer: current state and future promise
Lewis A Chodosh Breast Cancer Research 2011, 13:113 (1 November 2011)
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Cancer's sweet tooth for serine
Ji Luo Breast Cancer Research 2011, 13:317 (28 November 2011)
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New insights into the role of androgen and oestrogen receptors in molecular apocrine breast tumours
Richard D Iggo Breast Cancer Research 2011, 13:318 (8 December 2011)
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Review |
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Mutations in the phosphatidylinositol 3-kinase pathway: role in tumor progression and therapeutic implications in breast cancer
Todd W Miller, Brent N Rexer, Joan T Garrett, Carlos L Arteaga Breast Cancer Research 2011, 13:224 (1 November 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Clinical relevance and biology of circulating tumor cells
Natalia Bednarz-Knoll, Catherine Alix-Panabières, Klaus Pantel Breast Cancer Research 2011, 13:228 (1 November 2011)
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Mammographic density and breast cancer risk: current understanding and future prospects
Norman F Boyd, Lisa J Martin, Martin J Yaffe, Salomon Minkin Breast Cancer Research 2011, 13:223 (1 November 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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The microenvironment in breast cancer progression: biology and implications for treatment
Andrew E Place, Sung Jin Huh, Kornelia Polyak Breast Cancer Research 2011, 13:227 (1 November 2011)
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Epigenetics in breast cancer: what's new?
Yi Huang, Shweta Nayak, Rachel Jankowitz, Nancy E Davidson, Steffi Oesterreich Breast Cancer Research 2011, 13:225 (1 November 2011)
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Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticity
David J Drasin, Tyler P Robin, Heide L Ford Breast Cancer Research 2011, 13:226 (1 November 2011)
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Luminal-B breast cancer and novel therapeutic targets
Ben Tran, Philippe L Bedard Breast Cancer Research 2011, 13:221 (30 November 2011)
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β1-integrins signaling and mammary tumor progression in transgenic mouse models: implications for human breast cancer
Hicham Lahlou, William J Muller Breast Cancer Research 2011, 13:229 (30 November 2011)
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'Omic approaches to preventing or managing metastatic breast cancer
Obi L Griffith, Joe W Gray Breast Cancer Research 2011, 13:230 (8 December 2011)
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Research |
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Protein expression, survival and docetaxel benefit in node-positive breast cancer treated with adjuvant chemotherapy in the FNCLCC - PACS 01 randomized trial
Jocelyne Jacquemier, Jean-Marie Boher, Henri Roche, Benjamin Esterni, Daniel Serin, Pierre Kerbrat, Fabrice Andre, Pascal Finetti, Emmanuelle Charafe-Jauffret, Anne-Laure Martin, Mario Campone, Patrice Viens, Daniel Birnbaum, Frédérique Penault-Llorca, François Bertucci Breast Cancer Research 2011, 13:R109 (1 November 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2
Anna Mulligan, Fergus J Couch, Daniel Barrowdale, Susan M Domchek, Diana Eccles, Heli Nevanlinna, Susan J Ramus, Mark Robson, Mark Sherman, Amanda B Spurdle, Barbara Wappenschmidt, Andrew Lee, Lesley McGuffog, Sue Healey, Olga M Sinilnikova, Ramunas Janavicius, Thomas vO Hansen, Finn C Nielsen, Bent Ejlertsen, Ana Osorio, Iván Muñoz-Repeto, Mercedes Durán, Javier Godino, Maroulio Pertesi, Javier Benítez, Paolo Peterlongo, Siranoush Manoukian, Bernard Peissel, Daniela Zaffaroni, Elisa Cattaneo et al.
Breast Cancer Research 2011, 13:R110 (2 November 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Loss of interferon regulatory factor 5 (IRF5) expression in human ductal carcinoma correlates with disease stage and contributes to metastasis
Xiaohui Bi, Meera Hameed, Neena Mirani, Erica Pimenta, Jason Anari, Betsy J Barnes Breast Cancer Research 2011, 13:R111 (4 November 2011)
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ARTEMIN synergizes with TWIST1 to promote metastasis and poor survival outcome in patients with ER negative mammary carcinoma
Arindam Banerjee, Zheng-Sheng Wu, PengXu Qian, Jian Kang, Vijay Pandey, Dong-Xu Liu, Tao Zhu, Peter E Lobie Breast Cancer Research 2011, 13:R112 (7 November 2011)
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Sensitization of epithelial growth factor receptors by nicotine exposure to promote breast cancer cell growth
Takashi Nishioka, Hyun-Seok Kim, Ling-Yu Luo, Yi Huang, Jinjin Guo, Chang Yan Chen Breast Cancer Research 2011, 13:R113 (15 November 2011)
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Single nucleotide polymorphisms associated with risk for contralateral breast cancer in the Women's Environment, Cancer, and Radiation Epidemiology (WECARE) Study
Sharon N Teraoka, Jonine L Bernstein, Anne S Reiner, Robert W Haile, Leslie Bernstein, Charles F Lynch, Kathleen E Malone, Marilyn Stovall, Marinela Capanu, Xiaolin Liang, Susan A Smith, Josyf Mychaleckyj, Xuanlin Hou, Lene Mellemkjaer, John D Boice, Ashley Siniard, David Duggan, Duncan C Thomas, The WECARE Study Collaborative Group, and Patrick Concannon Breast Cancer Research 2011, 13:R114 (17 November 2011)
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Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasion
Bernadette C Victor, Arulselvi Anbalagan, Mona M Mohamed, Bonnie F Sloane, Dora Cavallo-Medved Breast Cancer Research 2011, 13:R115 (17 November 2011)
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miRNA-34b as a tumor suppressor in estrogen-dependent growth of breast cancer cells
Yee-Ming Lee, Jen-Yi Lee, Chao-Chi Ho, Qi-Sheng Hong, Sung-Liang Yu, Chii-Ruey Tzeng, Pan-Chyr Yang, Huei-Wen Chen Breast Cancer Research 2011, 13:R116 (23 November 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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A different immunologic profile characterizes patients with HER-2-overexpressing and HER-2-negative locally advanced breast cancer: implications for immune-based therapies
Elena Muraro, Debora Martorelli, Elisa Turchet, Gianmaria Miolo, Simona Scalone, Elisa Comaro, Renato Talamini, Katy Mastorci, Davide Lombardi, Tiziana Perin, Antonino Carbone, Andrea Veronesi, Diana Crivellari, Riccardo Dolcetti Breast Cancer Research 2011, 13:R117 (23 November 2011)
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Cancer stem cell markers in breast cancer: pathological, clinical and prognostic significance
H Raza Ali, Sarah-Jane Dawson, Fiona M Blows, Elena Provenzano, Paul D Pharoah, Carlos Caldas Breast Cancer Research 2011, 13:R118 (23 November 2011)
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CHEK2 contribution to hereditary breast cancer in non-BRCA families
Alexis Desrichard, Yannick Bidet, Nancy Uhrhammer, Yves-Jean Bignon Breast Cancer Research 2011, 13:R119 (24 November 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Targeting cholesterol-rich microdomains to circumvent tamoxifen-resistant breast cancer
Richa Tiwary, Weiping Yu, Linda A deGraffenried, Bob G Sanders, Kimberly Kline Breast Cancer Research 2011, 13:R120 (24 November 2011)
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Different mechanisms for resistance to trastuzumab versus lapatinib in HER2- positive breast cancers -- role of estrogen receptor and HER2 reactivation
Yen-Chao Wang, Gladys Morrison, Ryan Gillihan, Jun Guo, Robin M Ward, Xiaoyong Fu, Maria F Botero, Nuala A Healy, Susan G Hilsenbeck, Gail Phillips, Gary C Chamness, Mothaffar F Rimawi, C Kent Osborne, Rachel Schiff Breast Cancer Research 2011, 13:R121 (28 November 2011)
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Editor’s summary
Combined lapatinib and trastuzumab therapy may improve outcomes in patients with human epidermal growth factor 2 (HER2)-positive breast cancer; adding estrogen receptor inhibition may be optimal in some patients.
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Advantages of adjuvant chemotherapy for patients with triple-negative breast cancer at Stage II: usefulness of prognostic markers E-cadherin and Ki67
Shinichiro Kashiwagi, Masakazu Yashiro, Tsutomu Takashima, Naoki Aomatsu, Katsumi Ikeda, Yoshinari Ogawa, Tetsuro Ishikawa, Kosei Hirakawa Breast Cancer Research 2011, 13:R122 (30 November 2011)
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Anti-tumor activity and toxicokinetics analysis of MGAH22, an anti-HER2 monoclonal antibody with enhanced Fcγ receptor binding properties
Jeffrey L Nordstrom, Sergey Gorlatov, Wenjun Zhang, Yinhua Yang, Ling Huang, Steve Burke, Hua Li, Valentina Ciccarone, Tengfei Zhang, Jeffrey Stavenhagen, Scott Koenig, Stanford J Stewart, Paul A Moore, Syd Johnson, Ezio Bonvini Breast Cancer Research 2011, 13:R123 (30 November 2011)
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Activator protein 1 (AP-1) contributes to EpCAM-dependent breast cancer invasion
Narendra V Sankpal, John D Mayfield, Mike W Willman, Timothy P Fleming, William E Gillanders Breast Cancer Research 2011, 13:R124 (1 December 2011)
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Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases
Barbara Adamo, Allison M Deal, Emily Burrows, Joseph Geradts, Erika Hamilton, Kimberly L Blackwell, Chad Livasy, Karen Fritchie, Aleix Prat, J Harrell, Matthew G Ewend, Lisa A Carey, C Miller, Carey K Anders Breast Cancer Research 2011, 13:R125 (1 December 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer
Nathan R West, Katy Milne, Pauline T Truong, Nicol Macpherson, Brad H Nelson, Peter H Watson Breast Cancer Research 2011, 13:R126 (8 December 2011)
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Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2
Nyam-Osor Chimge, Sanjeev K Baniwal, Gillian H Little, Yi-bu Chen, Michael Kahn, Debu Tripathy, Zea Borok, Baruch Frenkel Breast Cancer Research 2011, 13:R127 (9 December 2011)
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Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis
Lorena Hernandez, Marco AO Magalhaes, Salvatore J Coniglio, John S Condeelis, Jeffrey E Segall Breast Cancer Research 2011, 13:R128 (9 December 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Landscape of somatic allelic imbalances and copy number alterations in HER2-amplified breast cancer
Johan Staaf, Göran Jönsson, Markus Ringnér, Bo Baldetorp, Åke Borg Breast Cancer Research 2011, 13:R129 (14 December 2011)
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Variants on the promoter region of PTEN affect breast cancer progression and patient survival
Tuomas Heikkinen, Dario Greco, Liisa M Pelttari, Johanna Tommiska, Pia Vahteristo, Päivi Heikkilä, Carl Blomqvist, Kristiina Aittomäki, Heli Nevanlinna Breast Cancer Research 2011, 13:R130 (15 December 2011)
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A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines
Teresa Puig, Helena Aguilar, Sílvia Cufí, Glòria Oliveras, Carlos Turrado, Sílvia Ortega-Gutiérrez, Bellinda Benhamú, María López-Rodríguez, Ander Urruticoechea, Ramon Colomer Breast Cancer Research 2011, 13:R131 (16 December 2011)
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A genome-wide linkage study of mammographic density, a risk factor for breast cancer
Celia MT Greenwood, Andrew D Paterson, Linda Linton, Irene L Andrulis, Carmel Apicella, Apostolos Dimitromanolakis, Valentina Kriukov, Lisa J Martin, Ayesha Salleh, Elena Samiltchuk, Rashmi V Parekh, Melissa C Southey, Esther M John, John L Hopper, Norman F Boyd, Johanna M Rommens Breast Cancer Research 2011, 13:R132 (21 December 2011)
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Lack of EGFR-activating mutations in European patients with triple-negative breast cancer could emphasise geographic and ethnic variations in breast cancer mutation profiles
William Jacot, Evelyne Lopez-Crapez, Simon Thezenas, Romain Senal, Frédéric Fina, Frédéric Bibeau, Gilles Romieu, Pierre-Jean Lamy Breast Cancer Research 2011, 13:R133 (22 December 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Potential geographic and ethnic variations in the prevalence of EGFR mutations in triple negative breast cancer have implications for clinical trial design for anti-estrogen growth factor receptor (EGFR) therapies.
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Long-term prognosis of breast cancer detected by mammography screening or other methods
Tiina Lehtimäki, Mikael Lundin, Nina Linder, Harri Sihto, Kaija Holli, Taina Turpeenniemi-Hujanen, Vesa Kataja, Jorma Isola, Heikki Joensuu, Johan Lundin Breast Cancer Research 2011, 13:R134 (28 December 2011)
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Editor’s summary
Patients with breast cancer detected in mammography screening have a more favorable prognosis than those diagnosed outside a screening program and this should be taken into account in order to avoid over-treatment of screen-detected patients.
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