Review

Breast cancer intra-tumor heterogeneity

Luciano G Martelotto , Charlotte KY Ng , Salvatore Piscuoglio , Britta Weigelt and Jorge S Reis-Filho

Breast Cancer Research 2014, 16:210 (20 May 2014)

Reis-Filho and colleagues review the models that explain tumor heterogeneity, the causes of intra-tumor genetic diversity and their impact on our understanding, assessment and management of breast cancer.

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