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Allelic loss on chromosome band 18p11.3 occurs early and reveals heterogeneity in breast cancer progression
Kanokwan Kittiniyom, Karen M Gorse, Fabienne Dalbegue, Jack H Lichy, Jeffery K Taubenberger, Irene F Newsham Breast Cancer Res 2001, 3:192-198 (12 February 2001)
Abstract | Full text | PDF | PubMed |
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Editor’s summary
This study correlates heterogeneity with loss of heterozygosity (LOH) on chromosome 18p11. In breast cancer patients with ductal carcinoma, significant LOH (56%) occurred, suggesting 18p11 alteration is a common and early event in breast disease.
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