Breast Cancer Research

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Applications of microarray technology in breast cancer research

Colin S Cooper

Author Affiliations

The Institute of Cancer Research, Sutton, Surrey, UK

Breast Cancer Res 2001, 3:158-175 doi:10.1186/bcr291

Published: 20 March 2001

Abstract

Microarrays provide a versatile platform for utilizing information from the Human Genome Project to benefit human health. This article reviews the ways in which microarray technology may be used in breast cancer research. Its diverse applications include monitoring chromosome gains and losses, tumour classification, drug discovery and development, DNA resequencing, mutation detection and investigating the mechanism of tumour development.

Keywords:
drug discovery; genetic gains and losses; microarrays; microarray design; mutation detection; tumour classification