Table 2 |
||||||
|
Univariate analysis of prognostic factors related to axillary lymph node invasion |
||||||
| Factor |
Variable |
No. of women |
Positive nodes (%) |
Odds ratio |
95% CI |
P |
|
|
||||||
| Histology |
Ductal |
45 |
29 (64%) |
1.00 |
||
| Other |
7 |
6 (86%) |
3.31 |
0.37-29.97 |
0.287 |
|
| Tumor mass |
Single |
36 |
21 (58%) |
1.00 |
||
| Other |
16 |
14 (88%) |
5.00 |
0.99-25.34 |
0.052 |
|
| Clinical response |
No |
13 |
(77%) |
1.00 |
||
| Yes |
39 |
25 (64%) |
0.54 |
0.13-2.28 |
0.398 |
|
| ER |
Negative |
22 |
16 (73%) |
1.00 |
||
| Positive |
30 |
19 (63%) |
0.65 |
0.20-2.14 |
0.477 |
|
| PR |
Negative |
28 |
21 (75%) |
1.00 |
||
| Positive |
24 |
14 (58%) |
0.47 |
0.14-1.52 |
0.205 |
|
| c-erb-B2 |
Negative |
37 |
24 (64%) |
1.00 |
||
| Positive |
15 |
11 (73%) |
1.49 |
0.37-5.62 |
0.557 |
|
| 53 |
Negative |
34 |
24 (71%) |
1.00 |
||
| Positive |
18 |
11 (61%) |
0.65 |
0.20-2.18 |
0.489 |
|
| Ki67 |
<20% |
17 |
6 (35%) |
1.00 |
||
| ≥ 20% |
33 |
27 (82%) |
8.25 |
2.18-31.23 |
0.002 |
|
| MDR1 (IHC) |
Negative |
14 |
8 (57%) |
1.00 |
||
| Positive |
9 |
7 (78%) |
2.63 |
0.39-17.46 |
0.318 |
|
| LRP |
Negative |
8 |
3 (38%) |
1.00 |
||
| Positive |
23 |
17 (74%) |
4.72 |
0.86-26.04 |
0.075 |
|
| MDR1 (RT-PCR) |
Negative |
24 |
13 (54%) |
1.00 |
||
| Positive |
22 |
18 (82%) |
3.81 |
0.99-14.67 |
0.052 |
|
| MDR1 (RT-PCR) |
Both negative |
8 |
3 (38%) |
1.00 |
||
| and LRP combined |
||||||
| LRP+ MDR1- |
7 |
4 (57%) |
2.22 |
0.28-17.63 |
0.450 |
|
| Both positive |
15 |
13 (87%) |
10.83 |
1.37-85.43 |
0.024 |
|
|
|
||||||
|
CI, confidence interval; ER, estrogen receptor; PR, progesterone receptor; RT-PCR, reverse-transcriptase-mediated polymerase chain reaction. |
||||||
|
Schneider et al. Breast Cancer Res 2001 3:183 doi:10.1186/bcr293 |
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