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Reversal effects of nomegestrol acetate on multidrug resistance in adriamycin-resistant MCF7 breast cancer cell line
Jie Li, Liang-Zhong Xu, Kai-Ling He, Wei-Jian Guo, Yun-Hong Zheng, Peng Xia, Ying Chen Breast Cancer Res 2001, 3:253-263 (2 April 2001)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Classical agents which reverse multidrug resistance are highly toxic. Studies in MCF7 breast cancer cells demonstrate that nomegestrol, which has strong reversal activity with very low toxicity, is a promising drug for clinical application.
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