Table 4 |
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|
ORs and 95% CIs for combinations of ADRB2 and ADRB3 genetic polymorphisms |
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|
Combined genotypes |
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|
|
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|
Patients |
Control |
ORs for breast |
Age-adjusted ORs |
Mean BMI of control |
||
|
ADRB2 |
ADRB3 |
(n) |
individuals (n) |
cancer (95% CI) |
for breast cancer (95% CI) |
individuals ± SD |
|
|
||||||
|
Gln/Gln |
Trp/Trp |
119 |
98 |
1.00 |
1.00 |
22.3 ± 3.0 |
|
Gln/Gln |
/Arg |
56 |
52 |
0.89 (0.56-1.41) |
0.88 (0.55-1.41) |
22.1 ± 2.8 |
|
/Glu |
Trp/Trp |
21 |
23 |
0.75 (0.39-1.44) |
0.76 (0.39-1.46) |
22.4 ± 3.1 |
|
/Glu |
/Arg |
4 |
9 |
0.37 (0.11-1.23) |
0.32 (0.10-1.10) |
22.2 ± 2.9 |
|
|
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|
The total number of cases was 200, and that of control individuals was 182. /Arg, a combination of Trp/Arg and Arg/Arg; /Glu, a combination of Gln/Glu and Glu/Glu. |
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|
Huang et al. Breast Cancer Res 2001 3:264 doi:10.1186/bcr304 |
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