Table 1 |
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|
Risk factors for breast cancer derived from univariate analysis |
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|
Number (%)* |
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|
|
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|
Parameter |
Cases (n = 286) |
Controls (n = 249) |
OR (95% CI) |
P |
|
|
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|
Age groups (years) |
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|
= 39 |
87 (30.4) |
101 (40.6) |
1.00 (ref.) |
|
|
40-49 |
84 (29.4) |
68 (27.3) |
1.43 (0.93-2.20) |
0.10 |
|
50-59 |
57 (19.9) |
44 (17.7) |
1.50 (0.92-2.45) |
0.10 |
|
= 60 |
58 (20.3) |
36 (14.5) |
1.87 (1.13-3.10) |
0.02 |
|
Mean ± SD |
47.5 (12.8) |
44.2 (13.2) |
||
|
Median (range) |
46.0 (24-81) |
43.0 (23-80) |
||
|
Educational level |
||||
|
Illiterate |
87 (30.4) |
91 (36.5) |
1.00 (ref.) |
|
|
Primary |
113 (39.5) |
100 (40.2) |
1.18 (0.79-1.76) |
0.41 |
|
Secondary |
60 (21.0) |
42 (16.9) |
1.49 (0.91-2.44) |
0.11 |
|
University |
26 (9.1) |
16 (6.4) |
1.70 (0.85-3.38) |
0.13 |
|
Marital status |
||||
|
Married |
205 (71.7) |
209 (83.9) |
1.00 (ref.) |
|
|
Widowed/divorced |
56 (19.6) |
34 (13.7) |
1.68 (1.05-2.68) |
0.03 |
|
Never married |
25 (8.7) |
6 (2.4) |
4.25 (1.71-10.57) |
0.002 |
|
Family history of breast cancer |
||||
|
No |
267 (93.4) |
243 (97.6) |
1.00 (ref.) |
|
|
Yes |
19 (6.6) |
6 (2.4) |
2.87 (1.13-7.30) |
0.03 |
|
Age at menarche (years) |
||||
|
= 12 |
72 (25.2) |
62 (24.9) |
1.20 (0.74-1.95) |
0.47 |
|
13 |
78 (27.3) |
63 (25.3) |
1.28 (0.79-2.1) |
0.32 |
|
14 |
74 (25.9) |
60 (24.1) |
1.27 (0.78-2.1) |
0.33 |
|
= 15 |
62 (21.7) |
64 (25.7) |
1.00 (ref.) |
|
|
Mean ± SD |
13.4 (1.5) |
13.5 (1.7) |
||
|
Median (range) |
13.0 (9-18) |
13.0 (9-19) |
||
|
Parity |
||||
|
Parous |
249 (87.1) |
235 (94.4) |
1.00 (ref.) |
|
|
Nulliparous |
37 (12.9) |
14 (5.6) |
2.78 (1.45-5.35) |
0.002 |
|
Age at first full term pregnancy (years) |
||||
|
<20 |
127 (51.0) |
131 (55.7) |
1.00 (ref.) |
|
|
20-24 |
71 (28.5) |
72 (30.6) |
1.02 (0.68-1.53) |
0.93 |
|
25-29 |
39 (15.7) |
27 (11.5) |
1.49 (0.86-2.58) |
0.15 |
|
= 30 |
12 (4.8) |
5 (2.1) |
2.47 (0.84-7.22) |
0.10 |
|
Mean ± SD |
20.5 (5.2) |
19.4 (4.3) |
||
|
Median (range) |
19.0 (11-45) |
19.0 (10-35) |
||
|
Age at last full term pregnancy (years) |
||||
|
= 29 |
82 (32.9) |
85 (36.2) |
1.00 (ref.) |
|
|
30-34 |
69 (27.7) |
70 (29.8) |
1.02 (0.65-1.60) |
0.92 |
|
35-39 |
62 (24.9) |
49 (20.9) |
1.31 (0.81-2.12) |
0.27 |
|
= 40 |
36 (14.5) |
31 (13.2) |
1.20 (0.68-2.12) |
0.52 |
|
Mean ± SD |
32.5 (6.4) |
31.6 (6.9) |
||
|
Median (range) |
32.0 (17-49) |
32.0 (15-51) |
||
|
Menopausal status |
||||
|
Premenopausal |
186 (65.0) |
180 (72.3) |
1.00 (ref.) |
|
|
Postmenopasual |
100 (35.0) |
69 (27.7) |
1.40 (0.97-2.03) |
0.07 |
|
Age at menopause (years) |
||||
|
<50 |
42 (42) |
37 (53.6) |
1.00 (ref.) |
|
|
= 50 |
58 (58) |
32 (46.4) |
1.60 (0.86-2.96) |
0.14 |
|
Mean ± SD |
49.9 (4.9) |
48.0 (5.2) |
||
|
Median (range) |
50.0 (36-70) |
48.0 (36-60) |
||
|
Oral contraceptive use |
||||
|
No |
279 (97.6) |
240 (96.4) |
1.00 (ref.) |
|
|
Yes |
7 (2.4) |
9 (3.6) |
0.67 (0.25-1.82) |
0.43 |
|
|
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|
*Unless otherwise stated. CI, confidence interval; OR, odds ratio. |
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|
Ebrahimi et al. Breast Cancer Res 2002 4:R10 doi:10.1186/bcr454 |
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