Correction

Correction: Functional and molecular characterisation of mammary side population cells

Azra J Alvi1, Helen Clayton1, Chirag Joshi2, Tariq Enver2, Alan Ashworth1, Maria d M Vivanco1, Trevor C Dale3 and Matthew J Smalley34

Author Affiliations

1 Breakthrough Toby Robins Breast Cancer Centre, Institute of Cancer Research, London, UK

2 Section of Gene Function and Regulation, Institute of Cancer Research, London, UK

3 Section of Cell and Molecular Biology, Institute of Cancer Research, London, UK

4 Current address: Division of Molecular Genetics, Netherlands Cancer Institute, Amsterdam, The Netherlands

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Breast Cancer Res 2003, 5:E1  doi:10.1186/bcr563

The electronic version of this article is the complete one and can be found online at: http://breast-cancer-research.com/content/5/1/E1


Published:4 December 2002

© 2003 BioMed Central Ltd

Correction

It has been brought to our attention that there was an inaccuracy in the above article [1]. In the discussion section the authors state that "One of the assumptions underlying mammary transplant studies is that mammary outgrowths at limiting dilution are clonal (14,000–20,000 cells per cleared fat pad)" and they attribute this to reference 21 "Smith GH: Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype. Breast Cancer Res Treat 1996, 39:21–31" [2]. In the paper by Smith no claim of clonality is made, rather it is stated that it is not known whether the simultaneous development of both lobular and ductal phenotypes indicates cooperative interaction between the two epithelial progenitors or signals the presence of a third progenitor type capable of producing both ductular and lobular committed daughters. It is, therefore, incorrect that the assumption of clonality based on limiting dilution has been attributed to Gilbert Smith.

Correction

References

  1. Alvi A, Clayton H, Joshi C, Enver T, Ashworth A, Vivanco MdM, Dale TC, Smalley MJ: Functional and molecular characterisation of mammary side population cells.

    Breast Cancer Res 2003, 5:R1-R8. PubMed Abstract | BioMed Central Full Text | PubMed Central Full Text OpenURL

  2. Smith GH: Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype.

    Breast Cancer Res Treat 1996, 39:21-31. PubMed Abstract OpenURL