Breast cancer cell lines: friend or foe?
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* Corresponding author: Valerie Speirs v.speirs@leeds.ac.uk
Breast Cancer Res 2003, 5:89-95 doi:10.1186/bcr577
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BioMed Central: 12 citations
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Review
Choosing the right cell line for breast cancer research Deborah L Holliday, Valerie Speirs Breast Cancer Research 2011, 13:215 (12 August 2011) |
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Research article
Diana Connolly, Zhixia Yang, Maria Castaldi, Nichelle Simmons, Maja H Oktay, Salvatore Coniglio, Melissa J Fazzari, Pascal Verdier-Pinard, Cristina Montagna Breast Cancer Research 2011, 13:R76 (10 August 2011) |
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Research
Discovery of pathway biomarkers from coupled proteomics and systems biology methods Fan Zhang, Jake Y Chen BMC Genomics 2010, 11(Suppl 2):S12 (2 November 2010) |
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Primary research
NUCKS overexpression in breast cancer Yiannis Drosos, Mirsini Kouloukoussa, Anne Østvold, Kirsten Grundt, Nikos Goutas, Dimitrios Vlachodimitropoulos, Sophia Havaki, Panagoula Kollia, Christos Kittas, Evangelos Marinos, Vassiliki Aleporou-Marinou Cancer Cell International 2009, 9:19 (10 August 2009) |
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Research article
Jian Li, Fei Gao, Ning Li, Shengting Li, Guangliang Yin, Geng Tian, Shangang Jia, Kai Wang, Xiuqing Zhang, Huanming Yang, Anders Nielsen, Lars Bolund BMC Genomics 2009, 10:223 (13 May 2009) |
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Primary research
Chao Shen, Meijia Gu, Dan Liang, Lixia Miao, Liu Hu, Congyi Zheng, Jiakuan Chen Cancer Cell International 2009, 9:2 (2 January 2009) |
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Research article
Chris Cheadle, Maria Nesterova, Tonya Watkins, Kathleen C Barnes, John C Hall, Antony Rosen, Kevin G Becker, Yoon S Cho-Chung BMC Medical Genomics 2008, 1:43 (26 September 2008) Overexpression of the regulatory subunit of cAMP-dependent protein kinase (PKA) in ovarian cancer cells causes hyperproliferation for the RI isoform and differentiation for RII, suggesting that PKA may be pivotal in disease progression.
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Research article
PMC42, a breast progenitor cancer cell line, has normal-like mRNA and microRNA transcriptomes Anna Git, Inmaculada Spiteri, Cherie Blenkiron, Mark J Dunning, Jessica CM Pole, Suet-Feung Chin, Yanzhong Wang, James Smith, Frederick J Livesey, Carlos Caldas Breast Cancer Research 2008, 10:R54 (27 June 2008) Breast cancer cell line PMC42 is a good model for normal breast epithelium, providing a unique biological tool to study breast differentiation and the function of key miRNAs typically lost in cancer.
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Primary research
Sophia Havaki, Mirsini Kouloukoussa, Kawther Amawi, Yiannis Drosos, Leonidas D Arvanitis, Nikos Goutas, Dimitrios Vlachodimitropoulos, Stamatis D Vassilaros, Eleni Z Katsantoni, Irene Voloudakis-Baltatzis, Vassiliki Aleporou-Marinou, Christos Kittas, Evangelos Marinos Cancer Cell International 2007, 7:16 (2 October 2007) |
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Research article
Mark W Carlson, Vishwanath R Iyer, Edward M Marcotte BMC Genomics 2007, 8:117 (10 May 2007) |
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Research article
Natalija Eigėlienė, Pirkko Härkönen, Risto Erkkola BMC Cancer 2006, 6:246 (18 October 2006) |
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Technical advance
Heiko van der Kuip, Thomas E Mürdter, Maike Sonnenberg, Monika McClellan, Susanne Gutzeit, Andreas Gerteis, Wolfgang Simon, Peter Fritz, Walter E Aulitzky BMC Cancer 2006, 6:86 (7 April 2006) A tissue culture method, where cells remain viable and proliferate within their tissue environment, was successfully combined with a novel read out system to assess drug efficacy in breast cancer tissues.
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