Breast cancer cell lines: friend or foe?
1 Molecular Medicine Unit, University of Leeds, Leeds, UK
2 Breast Unit, St James's University Hospital, Leeds, UK
3 Academic Unit of Pathology, University of Leeds, Leeds, UK
Breast Cancer Res 2003, 5:89-95 doi:10.1186/bcr577Published: 3 February 2003
The majority of breast cancer research is conducted using established breast cancer cell lines as in vitro models. An alternative is to use cultures established from primary breast tumours. Here, we discuss the pros and cons of using both of these models in translational breast cancer research.