Table 1 |
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|
Distribution of breast cancer risk factors among controls in relation to the CYP17 genotype: Western New York Breast Cancer Study |
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Premenopausal (n = 86) |
Postmenopausal (n = 102) |
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|
|
|
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|
CYP17 genotype |
A1/A1 |
A1/A2 and A2/A2 |
A1/A1 |
A1/A2 and A2/A2 |
|
|
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|
Age at menarche |
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|
< 13 years |
15 (31) |
18 (49) |
18 (38) |
25 (46) |
|
≥ 13 years |
33 (69) |
20 (51) |
29 (62) |
30 (54) |
|
Difficulty getting pregnant |
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|
No |
38 (79) |
29 (76) |
32 (68)* |
47 (86)* |
|
Yes |
10 (21) |
9 (24) |
11 (23) |
8 (14) |
|
Age at first birth |
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|
< 25 years |
38 (79) |
28 (74) |
21 (45)* |
40 (73)* |
|
≥ 25 years |
10 (21) |
10 (26) |
26 (55) |
15 (27) |
|
Ever use oral contraceptives |
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|
No |
26 (54) |
19 (50) |
||
|
Yes |
22 (46) |
19 (50) |
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|
Family history of breast cancer |
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|
No |
45 (94) |
35 (92) |
43 (91) |
50 (91) |
|
Yes |
3 (6) |
3 (8) |
4 (9) |
5 (9) |
|
Age at menopause |
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|
< 48 years |
29 (62) |
29 (53) |
||
|
≥ 48 years |
18 (38) |
26 (47) |
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|
Ever use hormone replacement therapy |
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|
No |
32 (68) |
39 (71) |
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|
Yes |
15 (32) |
16 (29) |
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|
|
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|
Data presented as n (%). * Statistically significant (P < 0.05). |
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|
Ambrosone et al. Breast Cancer Res 2003 5:R45 doi:10.1186/bcr570 |
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