Table 1

Distribution of breast cancer risk factors among controls in relation to the CYP17 genotype: Western New York Breast Cancer Study

Premenopausal (n = 86)

Postmenopausal (n = 102)



CYP17 genotype

A1/A1

A1/A2 and A2/A2

A1/A1

A1/A2 and A2/A2


Age at menarche

< 13 years

15 (31)

18 (49)

18 (38)

25 (46)

≥ 13 years

33 (69)

20 (51)

29 (62)

30 (54)

Difficulty getting pregnant

No

38 (79)

29 (76)

32 (68)*

47 (86)*

Yes

10 (21)

9 (24)

11 (23)

8 (14)

Age at first birth

< 25 years

38 (79)

28 (74)

21 (45)*

40 (73)*

≥ 25 years

10 (21)

10 (26)

26 (55)

15 (27)

Ever use oral contraceptives

No

26 (54)

19 (50)

Yes

22 (46)

19 (50)

Family history of breast cancer

No

45 (94)

35 (92)

43 (91)

50 (91)

Yes

3 (6)

3 (8)

4 (9)

5 (9)

Age at menopause

< 48 years

29 (62)

29 (53)

≥ 48 years

18 (38)

26 (47)

Ever use hormone replacement therapy

No

32 (68)

39 (71)

Yes

15 (32)

16 (29)


Data presented as n (%). * Statistically significant (P < 0.05).

Ambrosone et al. Breast Cancer Res 2003 5:R45-R51   doi:10.1186/bcr570

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