Figure 2.

Excretion of CTX isoforms in healthy premenopausal (Pre) and postmenopausal controls (PM), and in breast cancer patients with hypercalcemia and bone metastases (HC+), in normocalcemic patients with bone metastases (NC+) and in normocalcemic patients without bone metastases (NC-). Shaded areas indicate mean ± 2 standard deviations for healthy premenopausal women. Bars indicate medians. αD = D-aspartyl peptide; αL = L-aspartyl peptide; βL = L-isoaspartyl peptide; CTX, crosslinked C-telopeptide of type I collagen.