|
The range and number of metastatic lymph nodes in node-positive breast cancers with different staining patterns for CXCR4 |
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| Staining pattern |
Staining pattern in diffuse type |
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|
|
|
|||||
| Lymph node metastasis |
Focal |
Diffuse |
P |
High |
Low |
P |
|
|
||||||
| Extent of metastasis |
||||||
| N1 |
3 |
17 |
0.021 |
5 |
12 |
0.025 |
| ≥ N2 |
9 |
9 |
8 |
1 |
||
| Number of metastatic nodes |
12.4 ± 10.4 |
5.1 ± 5.4 |
0.0071 |
7.8 ± 6.4 |
2.5 ± 1.8 |
0.0078 |
|
The difference between N1 and ≥ N2 was statistically significant between focal and diffuse types, and between high and low expression of CXCR4, by χ2 tests. The numbers of metastatic nodes were also significantly different between focal and diffuse types, and between high and low expression of CXCR4, by Student's t-test. N1, metastatic nodes were confined in low and mid axilla area; N2, metastatic nodes were detected at apical axilla area. | ||||||
Kato et al. Breast Cancer Res 2003 5:R144 doi:10.1186/bcr627 |
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