|
Observed and expected numbers of mutation carriers, as predicted by the LAMBDA model, for categories based on predicted range of probability of being a carrier |
||||
| Predicted range |
Numbers of carriers (percentage) |
|||
|
|
|
|||
| λ |
Probability (%) |
Number of women |
Observed |
Expected |
|
|
||||
| <-3.5 |
<2 |
128 |
5 (4%) |
2.1 (2%) |
| -3.5 to -2.25 |
2–10 |
117 |
12 (10%) |
7.2 (6%) |
| -2.0 to -1.25 |
10–25 |
84 |
11 (13%) |
13.4 (16%) |
| -1.0 to -0.25 |
25–50 |
59 |
14 (24%) |
20.1 (34%) |
| 0.0 to 0.75 |
50–75 |
30 |
16 (53%) |
18.2 (61%) |
| ≥ 1.0 |
≥ 75 |
6 |
6 (100%) |
5.1 (85%) |
| Total |
424 |
64 (15%) |
66.2 (16%) |
|
Apicella et al. Breast Cancer Res 2003 5:R206 doi:10.1186/bcr644 |
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