Table 1 |
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|
Clinicopathological variables according to c-erbB2 status |
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|
HER-2-negative |
HER-2-positive |
P |
Overall |
|
|
|
||||
|
Total |
54 |
13 |
67 |
|
|
Oestrogen receptor status |
||||
|
≤ 10 fmol/mg |
25 |
10 |
0.05* |
35 |
|
> 10 fmol/mg |
29 |
3 |
32 |
|
|
Node status |
||||
|
Negative |
36 |
8 |
0.73 |
44 |
|
Positive |
18 |
5 |
23 |
|
|
Histologic grade |
||||
|
Grade I |
4 |
0 |
0.48 |
4 |
|
Grade II |
17 |
5 |
22 |
|
|
Grade III |
22 |
7 |
29 |
|
|
'Other' |
11 |
1 |
12 |
|
|
Nottingham Prognostic Index |
||||
|
GPG score ≤ 3.4 |
4 |
1 |
0.61 |
6 |
|
MPG score 3.4–5.4 |
28 |
8 |
40 |
|
|
PPG score > 5.4 |
7 |
3 |
10 |
|
|
Age |
||||
|
< 50 years |
19 |
8 |
28 |
|
|
≥ 50 years |
35 |
5 |
39 |
|
|
Median (range) |
56 (32–80) |
46 (37–67) |
0.03* |
55 (32–80) |
|
Tumour size |
||||
|
≤ 2 cm |
15 |
4 |
19 |
|
|
> 2 cm |
39 |
9 |
48 |
|
|
Median (range) |
2.5 (1–5.5) |
2.6 (1–5.3) |
0.76 |
2.5 (1–5.5) |
|
|
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|
GPG, good prognostic group; MPG, moderate prognostic group; PPG, poor prognostic group. *Relationship reached significance (P ≤ 0.05). |
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|
Winters et al. Breast Cancer Res 2003 5:R242 doi:10.1186/bcr654 |
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