Table 1

Clinicopathological variables according to c-erbB2 status

HER-2-negative
 HER-2-positive
 P
 Overall
Total
 54
 13
67
Oestrogen receptor status



     ≤ 10 fmol/mg
 25
 10
 0.05*
 35
     > 10 fmol/mg
 29
 3
32
Node status



     Negative
 36
 8
 0.73
 44
     Positive
 18
 5
23
Histologic grade



     Grade I
 4
 0
 0.48
 4
     Grade II
 17
 5
22
     Grade III
 22
 7
29
     'Other'
 11
 1
12
Nottingham Prognostic Index



     GPG score ≤ 3.4
 4
 1
 0.61
 6
     MPG score 3.4–5.4
 28
 8
40
     PPG score > 5.4
 7
 3
10
Age



     < 50 years
 19
 8
28
     ≥ 50 years
 35
 5
39
     Median (range)
 56 (32–80)
 46 (37–67)
 0.03*
 55 (32–80)
Tumour size



     ≤ 2 cm
 15
 4
19
     > 2 cm
 39
 9
48
     Median (range)
 2.5 (1–5.5)
 2.6 (1–5.3)
 0.76
 2.5 (1–5.5)

GPG, good prognostic group; MPG, moderate prognostic group; PPG, poor prognostic group. *Relationship reached significance (P ≤ 0.05).

Winters et al. Breast Cancer Res 2003 5:R242   doi:10.1186/bcr654

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