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This article is part of the supplement: 24th Congress of the International Association for Breast Cancer Research. Advances in human breast cancer research: preclinical models

Oral presentation

Clinical breast cancer and estrogen

HK Chew

UC Davis Cancer Center, Sacramento, California, USA

from 24th Congress of the International Association for Breast Cancer Research. Advances in human breast cancer research: preclinical models
Sacramento, USA. 1-5 November 2003

Breast Cancer Res 2003, 5(Suppl 1):18doi:10.1186/bcr677

Published: 31 October 2003

Oral presentation

Endocrine therapy, targeting estrogen production or the estrogen receptor, is a crucial component in the treatment of breast cancer. This has been recognized for over a century. Ovarian ablation is the oldest form of endocrine therapy, first used in 1896. This presentation will review: the history of endocrine therapy in the treatment of breast cancer; endocrine strategies in premenopausal and postmenopausal women; data on the use of endocrine therapy in early breast cancer; new directions in the endocrine therapy of metastatic breast cancer; and clinical implications of HER2-neu status and endocrine therapy.

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