Table 2

Tumor and serum basic fibroblast growth factor (bFGF) in relation to clinical, pathological and biological characteristics in breast cancer patients


Tumor bFGF
Serum bFGF



Number of cases
% positive cells [median (range)]
P
Number of cases
Serum level (pg/ml) [median (range)]
P

Age






     51–70 years
41
45 (0–90)
0.25
46
2.2 (0.3–15.1)
0.40
     > 70 years
22
65 (5–100)

27
3.0 (0.4–26.6)

Histotype






     Ductal
54
55 (0–100)
0.68
60
2.2 (0.3–26.6)
0.90
     Others
9
60 (0–85)

13
2.3 (0.4–5.2)

Tumor size






     ≤ 2 cm
43
55 (5–100)
0.53
51
2.3 (0.3–26.6)
0.37
     > 2 cm
20
63 (5–100)

21
1.9 (0.4–11.1)

Node status






     Node-negative
30
63 (0–100)
0.69
35
2.5 (0.3–15.1)
0.43
     Node-positive
27
65 (0–100)

28
2.0 (0.5–26.6)

Grade






     1–2
38
62.5 (0–100)
0.99
42
2.3 (0.3–15.1)
0.57
     3
12
60 (5–100)

13
3.1 (1.5–26.6)

Steroid status






     ER-positive
43
45 (0–100)
0.43
49
2.2 (0.3–15.1)
0.32
     ER-negative
10
65 (5–95)

11
3.5 (1.8–11.1)

     PgR-positive
32
38 (0–100)
0.12
35
2.0 (0.4–8.6)
0.19
     PgR-negative
21
70 (5–95)

25
2.5 (0.3–15.1)


ER, estrogen receptor; PgR, progesterone receptor.

Granato et al. Breast Cancer Res 2004 6:R38   doi:10.1186/bcr745