|
Univariate analysis of factors influencing breast cancer specific survival |
|||
| Variable |
n |
Breast cancer deaths (n) |
P |
|
|
|||
| BRCA mutation |
|||
| Any |
56 |
18 |
0.0002 |
| None |
439 |
61 |
|
| BRCA1 mutation |
|||
| Mutation present |
43 |
16 |
< 0.0001 |
| Mutation absent |
439 |
61 |
|
| BRCA2 mutation |
|||
| Mutation present |
14 |
2 |
0.76 |
| Mutation absent |
439 |
61 |
|
| Tumor size |
|||
| ≤ 2 cm |
360 |
41 |
< 0.0001 |
| > 2 cm |
111 |
31 |
|
| Axillary node |
|||
| Negative |
290 |
31 |
< 0.0001 |
| Positive |
172 |
44 |
|
| Estrogen receptor |
|||
| Positive |
210 |
28 |
0.01 |
| Negative |
127 |
31 |
|
| Age at diagnosis (years) |
|||
| < 50 |
169 |
42 |
< 0.0001 |
| ≥ 50 |
326 |
37 |
|
| Chemotherapy |
|||
| Yes |
187 |
48 |
< 0.0001 |
| No |
279 |
30 |
|
| Tamoxifen |
|||
| Yes |
208 |
28 |
0.14 |
| No |
237 |
47 |
|
Robson et al. Breast Cancer Res 2004 6:R8 doi:10.1186/bcr658 |
|||