Table 4

Multivariate Cox regression models for disease-free survival and overall survival in patients with invasive ductal carcinoma and patients with invasive lobular carcinoma


DFS
OS



Parameter
RR (95% CI)
P
RR (95% CI)
P

Nodes




     0
1
<0.0001
1
<0.0001
     1–3
1.8 (1.6–1.9)

1.4 (1.3–1.5)

     >3
3.4 (3.1–3.6)

2.4 (2.2–2.5)

Tumor size (cm)




     ≤2
1
<0.0001
1
<0.0001
     2–5
1.5 (1.4–1.6)

1.4 (1.3–1.5)

     >5
1.9 (1.7–2.1)

2.0 (1.8–2.1)

Age (years)




     ≤50
1
0.0005
1
<0.0001
     >50
1.1 (1.0–1.2)

1.9 (1.7–2.0)

S-phase




     Low
1
<0.0001
1
<0.0001
     Intermediate
1.4 (1.3–1.5)

1.3 (1.2–1.3)

     High
1.5 (1.4–1.7)

1.4 (1.3–1.5)

PgR




     Positive
1
<0.0001
1
0.0014
     Negative
1.3 (1.2–1.4)

1.3 (1.2–1.4)

ER




     Positive
1
0.0017
1
0.048
     Negative
1.1 (1.0–1.2)

1.1 (1.0–1.2)


CI, confidence interval; DFS, disease-free survival; ER, estrogen receptor; OS, overall survival; PgR, progesterone receptor; RR, relative risk.

Arpino et al. Breast Cancer Res 2004 6:R149  

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