Table 5 |
||||
|
Multivariate Cox regression models for disease-free survival and overall survival in invasive lobular carcinoma patients |
||||
|
DFS |
OS |
|||
|
|
|
|||
|
Parameter |
RR (95% CI) |
P |
RR (95% CI) |
P |
|
|
||||
|
Nodes |
||||
|
0 |
1 |
<0.0001 |
1 |
<0.0001 |
|
1–3 |
2.2 (1.6–3.2) |
1.4 (1.1–1.9) |
||
|
>3 |
4.1 (2.9–5.7) |
2.2 (1.7–2.9) |
||
|
Tumor size (cm) |
||||
|
≤2 |
1 |
<0.0001 |
1 |
<0.0001 |
|
>2 |
1.9 (1.4–2.6) |
1.6 (1.3–2.1) |
||
|
Age (years) |
||||
|
≤50 |
- |
NS |
1 |
<0.0001 |
|
>50 |
- |
2.3 (1.7–3.1) |
||
|
S-phase |
||||
|
Low |
1 |
0.002 |
1 |
<0.0293 |
|
Intermediate–high |
1.7 (1.3–2.2) |
1.3 (1.0–1.6) |
||
|
PgR |
||||
|
Positive |
1 |
0.003 |
- |
NS |
|
Negative |
1.5 (1.1–1.9) |
- |
||
|
ER |
||||
|
Positive |
- |
NS |
1 |
0.0006 |
|
Negative |
- |
1.9 (1.3–2.8) |
||
|
Ploidy |
||||
|
Diploid |
1 |
0.03 |
- |
NS |
|
Aneuploid |
1.7 (1.3–2.2) |
- |
||
|
|
||||
|
CI, confidence interval; DFS, disease-free survival; ER, estrogen receptor; NS, not significant; OS, overall survival; PgR, progesterone receptor; RR, relative risk. |
||||
|
Arpino et al. Breast Cancer Res 2004 6:R149 |
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