|
Daily number of hot flushes and menopausal symptom score at baseline and after 12 months, and change from baseline to 12 months by treatment group |
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| Isoflavone (n = 45, n = 70)a |
Placebo (n = 54, n= 83)a |
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|
|
|
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| Baseline |
12 months |
Change |
Baseline |
12 months |
Change |
P for changeb |
|
| Mean daily number of hot flushes |
2.1 ± 2.7 |
1.2 ± 2.3 |
-0.8 ± 2.1 |
2.5 ± 3.0 |
1.5 ± 2.0 |
-1.0 ± 1.8 |
0.41 |
| Menopausal symptom score |
4.3 ± 4.3 |
3.4 ± 4.1 |
-0.9 ± 4.1 |
4.3 ± 4.3 |
3.5 ± 3.8 |
-0.8 ± 2.8 |
0.88 |
|
Analyses based on women who reported hot flushes or menopausal symptoms in one or both diaries. Values are expressed as means ± standard deviation. a Shown in parentueses are the number of women with hot flushes and number of women with any menopausal symptoms, respectively. bP value for difference between treatment groups for change. | |||||||
Atkinson et al. Breast Cancer Res 2004 6:R170 |
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