Figure 3.

Relationships between p14^ARF and Hdm2 localisation and overall survival. Overall survival curves according to nuclear p14^ARF (a), cytoplasmic p14^ARF (b) and cytoplasmic Hdm2 (c), with patient numbers and deaths in parentheses. The classification of 'present' or 'absent' p14^ARF or Hdm2 expression was determined by an MQS of 3 or more to define positivity, compared with an MQS of <3 to define absent expression. Patient numbers reflect the exclusion of six local tumour recurrences from the analysis of patient outcome and include only recorded deaths in 23 patients. P values are given for the log ranks that reached significance.