Figure 7.

Ductal carcinoma in situ (DCIS), comedo, solid and cribriform type (patient 18). (a) Tumor section (hematoxylin & eosin, × 25). Regions of DCIS (arrowheads), within normal breast tissue (asterisk). (b) In vitro ^99mTc-(V)DMSA autoradiogram of the same section (× 25). Distribution of the radioactivity in the same tumor section. The sites of intense tracer uptake (curved arrow) appear darker. (c) Overlay of stained tumor section and autoradiogram. The histologically detected lesion is well correlated with the tissue sites of intense ^99mTc-(V)DMSA uptake.