Table 1

Characteristics of mastectomy-treated breast cancer patients in the Surveillance, Epidemiology, and End Results (SEER) Breast Implant Surveillance Study, 1983–1989

Characteristic

All eligible patients (n = 5862)

Study responders only (n = 4968)


Nonresponders (n = 894)

Responders (n = 4968)

P value

Women with breast implants (n = 1018)

Women without breast implants (n = 3950)

P value



n

%

n

%

n

%

n

%


SEER region

San Francisco–Oakland

468

52.4

1853

37.3

0.0001

416

40.9

1437

36.4

0.0001

Seattle–Puget Sound

190

21.3

1663

33.5

374

36.7

1078

27.3

Iowa

236

26.4

1452

29.2

228

22.4

1435

36.3

Year of diagnosis

1983

246

27.5

1102

22.2

0.0001

176

17.3

926

23.4

0.0003

1985

241

27.0

1152

23.2

244

24.0

908

23.0

1987

230

25.7

1405

28.3

319

31.3

1086

27.5

1989

177

19.8

1309

26.3

279

27.4

1030

26.1

Age at diagnosis

< 35 years

59

6.6

175

3.5

0.0001

88

8.6

87

2.2

0.0001

35–44 years

231

25.8

919

18.4

334

32.8

585

14.8

45–54 years

256

28.6

1545

31.1

370

36.4

1175

29.8

55–64 years

348

38.9

2329

46.9

226

22.2

2103

53.2

Mean age at diagnosis (years)

49.9

-

52.1

-

0.0001

46.7

-

53.4

-

0.0001

Race/ethnicity

Non-Hispanic White

670

74.9

4444

89.5

0.0001

959

94.2

3485

88.2

0.0001

Non-Hispanic Black

78

8.7

150

3.0

13

1.3

137

3.5

Hispanic

38

4.3

131

2.6

20

2.0

111

2.8

Asian/Pacific Islander

86

9.6

179

3.6

16

1.6

163

4.1

Other/unknown

22

2.5

64

1.3

10

1.0

54

1.4

Stage at diagnosis

In situ

78

8.7

567

11.4

0.04

199

19.6

368

9.3

0.0001

Localized

562

62.9

3141

63.2

601

59.0

2540

64.3

Regional

241

27.0

1209

24.3

211

20.7

998

25.3

Unstaged

13

1.5

51

1.0

7

0.7

44

1.1

Histology

Infiltrating ductal

687

76.9

3638

73.2

0.04

695

68.3

2943

74.5

0.0001

Lobular

44

4.9

364

7.3

106

10.4

258

6.5

Infiltrating ductal and lobular

35

3.9

195

3.9

54

5.3

141

3.6

Not otherwise specified/other

128

14.3

771

15.5

163

16.0

608

15.4

Grade

Well differentiated

17

1.9

150

3.0

0.02

29

2.9

121

3.1

0.91

Moderately differentiated

128

14.3

712

14.3

137

13.5

575

14.6

Poorly differentiated

144

16.1

824

6.6

169

16.6

655

16.6

Undifferentiated

17

1.9

185

3.7

39

3.8

146

3.7

Unknown grade

588

65.8

3097

62.3

644

63.3

2453

62.1

Number of primary tumors

One primary only

771

86.2

4001

80.5

0.0001

867

85.2

3134

79.3

0.0001

Two or more primaries

123

13.8

967

19.5

151

14.8

816

20.7

Radiation therapy during first course of treatment

No

814

91.1

4626

93.1

0.03

969

95.2

3657

92.6

0.01

Yes

80

9.0

333

6.7

48

4.7

285

7.2

Unknown

0

0

9

0.2

1

0.1

8

0.2

Vital statusa

Alive

538

60.2

3696

74.4

0.0001

867

85.2

2828

71.6

0.0001

Dead

356

39.8

1272

25.6

151

14.8

1122

28.4


aFinal date of follow-up, December 1999.

Le et al. Breast Cancer Res 2005 7:R184-R193   doi:10.1186/bcr974

Open Data