Table 1

Characteristics of mastectomy-treated breast cancer patients in the Surveillance, Epidemiology, and End Results (SEER) Breast Implant Surveillance Study, 1983–1989
Characteristic
 All eligible patients (n = 5862)
 Study responders only (n = 4968)


Nonresponders (n = 894)
 Responders (n = 4968)
 P value
 Women with breast implants (n = 1018)
 Women without breast implants (n = 3950)
 P value



n
 %
 n
 %
n
 %
 n
 %
SEER region









     San Francisco–Oakland
 468
 52.4
 1853
 37.3
 0.0001
 416
 40.9
 1437
 36.4
 0.0001
     Seattle–Puget Sound
 190
 21.3
 1663
 33.5
374
 36.7
 1078
 27.3
     Iowa
 236
 26.4
 1452
 29.2
228
 22.4
 1435
 36.3
Year of diagnosis









     1983
 246
 27.5
 1102
 22.2
 0.0001
 176
 17.3
 926
 23.4
 0.0003
     1985
 241
 27.0
 1152
 23.2
244
 24.0
 908
 23.0
     1987
 230
 25.7
 1405
 28.3
319
 31.3
 1086
 27.5
     1989
 177
 19.8
 1309
 26.3
279
 27.4
 1030
 26.1
Age at diagnosis









     < 35 years
 59
 6.6
 175
 3.5
 0.0001
 88
 8.6
 87
 2.2
 0.0001
     35–44 years
 231
 25.8
 919
 18.4
334
 32.8
 585
 14.8
     45–54 years
 256
 28.6
 1545
 31.1
370
 36.4
 1175
 29.8
     55–64 years
 348
 38.9
 2329
 46.9
226
 22.2
 2103
 53.2
Mean age at diagnosis (years)
 49.9
 -
 52.1
 -
 0.0001
 46.7
 -
 53.4
 -
 0.0001
Race/ethnicity









     Non-Hispanic White
 670
 74.9
 4444
 89.5
 0.0001
 959
 94.2
 3485
 88.2
 0.0001
     Non-Hispanic Black
 78
 8.7
 150
 3.0
13
 1.3
 137
 3.5
     Hispanic
 38
 4.3
 131
 2.6
20
 2.0
 111
 2.8
     Asian/Pacific Islander
 86
 9.6
 179
 3.6
16
 1.6
 163
 4.1
     Other/unknown
 22
 2.5
 64
 1.3
10
 1.0
 54
 1.4
Stage at diagnosis









     In situ
 78
 8.7
 567
 11.4
 0.04
 199
 19.6
 368
 9.3
 0.0001
     Localized
 562
 62.9
 3141
 63.2
601
 59.0
 2540
 64.3
     Regional
 241
 27.0
 1209
 24.3
211
 20.7
 998
 25.3
     Unstaged
 13
 1.5
 51
 1.0
7
 0.7
 44
 1.1
Histology









     Infiltrating ductal
 687
 76.9
 3638
 73.2
 0.04
 695
 68.3
 2943
 74.5
 0.0001
     Lobular
 44
 4.9
 364
 7.3
106
 10.4
 258
 6.5
     Infiltrating ductal and lobular
 35
 3.9
 195
 3.9
54
 5.3
 141
 3.6
     Not otherwise specified/other
 128
 14.3
 771
 15.5
163
 16.0
 608
 15.4
Grade









     Well differentiated
 17
 1.9
 150
 3.0
 0.02
 29
 2.9
 121
 3.1
 0.91
     Moderately differentiated
 128
 14.3
 712
 14.3
137
 13.5
 575
 14.6
     Poorly differentiated
 144
 16.1
 824
 6.6
169
 16.6
 655
 16.6
     Undifferentiated
 17
 1.9
 185
 3.7
39
 3.8
 146
 3.7
     Unknown grade
 588
 65.8
 3097
 62.3
644
 63.3
 2453
 62.1
Number of primary tumors









     One primary only
 771
 86.2
 4001
 80.5
 0.0001
 867
 85.2
 3134
 79.3
 0.0001
     Two or more primaries
 123
 13.8
 967
 19.5
151
 14.8
 816
 20.7
Radiation therapy during first course of treatment









     No
 814
 91.1
 4626
 93.1
 0.03
 969
 95.2
 3657
 92.6
 0.01
     Yes
 80
 9.0
 333
 6.7
48
 4.7
 285
 7.2
     Unknown
 0
 0
 9
 0.2
1
 0.1
 8
 0.2
Vital statusa









     Alive
 538
 60.2
 3696
 74.4
 0.0001
 867
 85.2
 2828
 71.6
 0.0001
     Dead
 356
 39.8
 1272
 25.6
151
 14.8
 1122
 28.4

aFinal date of follow-up, December 1999.

Le et al. Breast Cancer Res 2005 7:R184   doi:10.1186/bcr974