Table 1 |
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|
RNAi directed against c-Myc significantly inhibits MCF-7 cell growth in nude mice |
||||||||
| No. of cellsa |
pSilencer |
pSilencer–c-Myc |
||||||
|
|
||||||||
| Tumor weight (mg) |
Tumors |
Injections |
Latencyb (day) |
Tumor weight (mg) |
Tumors |
Injections |
Latencyb (day) |
|
|
|
||||||||
| 106 |
45–210 |
3 |
5 |
42–49 |
0 |
0 |
5 |
>56 |
| 2 × 106 |
145–2248 |
4 |
5 |
21–28 |
0 |
0 |
5 |
>35 |
|
|
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|
aNumber of cells transfected with the indicated plasmids that were injected subcutaneously, bilaterally into five nude mice. bThe time interval required for a palpable tumor to arise. |
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|
Wang et al. Breast Cancer Res 2005 7:R220 doi:10.1186/bcr975 |
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