Table 1 |
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|
Mammary fat pad model tumor take and metastasis |
||||||
| Cell line |
Experimental parameters |
Detected metastases |
||||
|
|
||||||
| Mouse strain |
n |
Take rate |
End-point (weeks) |
LN in vivo |
Lung ex vivo |
|
|
|
||||||
| D3H1 |
Nude |
9, 10 |
40–78% |
8–13 |
75–86% R, 0% L |
0–16% |
| Nude-beige |
6 |
66% |
13 |
67% R, 16% L |
0% |
|
| D3H2LN |
Nude |
9, 8 |
89–100% |
5 |
100% R, 0% L |
38% |
| Nude-beige |
8 |
75% |
9 |
100% R, 100% L |
67% |
|
|
|
||||||
|
L, left; LN, lymph node; R, right. |
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|
Jenkins et al. Breast Cancer Research 2005 7:R444 doi:10.1186/bcr1026 |
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