Table 3 |
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|
Effect of category of benign breast disease histology on breast cancer riska |
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| Benign breast disease category |
Cases No. (%) |
Controls No. (%) |
OR (95% CI)b |
OR (95% CI)c |
|
|
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| Nonproliferative |
69(24.5) |
474 (38.8) |
1.00 (Ref) |
1.00 (Ref) |
| Proliferative without atypia |
140 (49.7) |
623 (50.9) |
1.59 (1.16–2.18) |
1.54 (1.12–2.11) |
| Atypical hyperplasia |
73 (25.9) |
126 (10.3) |
4.54 (3.03–6.78) |
4.43 (2.93–6.69) |
| Total |
282 |
1,223 |
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|
|
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|
aNurses' Health Study I (1976 to 1994) and II (1989 to 1995). bAdjusted for age, year of biopsy, and follow-up interval. cAdjusted for age, year of biopsy, and follow-up interval, age at menarche, body mass index, weight change since age 18, age at first birth/parity, menopausal status/type of menopause, duration of postmenopausal hormone use. CI, confidence interval; OR, odds ratio; Ref, reference group for statistical comparisons. |
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|
Tamimi et al. Breast Cancer Research 2005 7:R555 doi:10.1186/bcr1039 |
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