Breast Cancer Research

official impact factor 5.79

Open Access

Inhibition of insulin-like growth factor-1 receptor signaling enhances growth-inhibitory and proapoptotic effects of gefitinib (Iressa) in human breast cancer cells

Anne Camirand, Mahvash Zakikhani, Fiona Young and Michael Pollak*

Breast Cancer Research 2005, 7:R570-R579 doi:10.1186/bcr1028

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Research article   Open Access

A moderate elevation of circulating levels of IGF-I does not alter ErbB2 induced mammary tumorigenesis

Robert K Dearth, Isere Kuiatse, Yu-Fen Wang, Lan Liao, Susan G Hilsenbeck, Powel H Brown, Jianming Xu, Adrian V Lee BMC Cancer 2011, 11:377 (25 August 2011)

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A selective eradication of human nonhereditary breast cancer cells by phenanthridine-derived polyADP-ribose polymerase inhibitors

Dana Inbar-Rozensal, Asher Castiel, Leonid Visochek, David Castel, Françoise Dantzer, Shai Izraeli, Malka Cohen-Armon Breast Cancer Research 2009, 11:R78 (9 November 2009)

Phenanthridine derived polyADP-ribose polymerase (PARP) inhibitors originally designed to protect cells from cell-death under stress conditions efficiently eradicate breast cancer cells without impairing normal proliferating or non-proliferating cells.

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The aromatase inhibitor letrozole and inhibitors of insulin-like growth factor I receptor synergistically induce apoptosis in in vitro models of estrogen-dependent breast cancer

Joanna Lisztwan, Astrid Pornon, Bin Chen, Shiuan Chen, Dean B Evans Breast Cancer Research 2008, 10:R56 (8 July 2008)