Table 1 |
|
|
Signaling molecules localized to mammary buds |
|
|
Epithelium |
Mesenchyme |
|
|
|
|
PTHrP |
PTH1R |
|
Wnts 10a, 10b, 6 |
Eda-A1 |
|
β-Catenin |
Wnt11, Wnt5a |
|
Axin2 |
Lef1 |
|
Lef1 |
β-Catenin |
|
Kremen 2 |
Fgf7 |
|
FGFR2b, FGFR1b |
MSX2 |
|
Fgfs 4,8,9,17 |
TBX2 |
|
Sonic Hedgehog, Indian Hedgehog |
Hoxa9, Hoxb9, Hoxc9 |
|
Gli2, Gli3, Ptc1 |
BMP4 |
|
BMP2 |
ER-α, ER-β |
|
Edar |
Androgen receptor |
|
MSX1, MSX2 |
Pdgfr |
|
Irx2 |
Tenascin C |
|
Lmx1b |
|
|
TBX3 |
|
|
PdgfA |
|
|
|
|
|
Edar, ectodysplasin receptor; FGF, fibroblast growth factor; Lef, lymphoid enhancing factor; Pdgfr, platelet-derived growth factor receptor; PTH1R, PTHrP receptor 1; PTHrP, parathyroid hormone related protein |
|
|
Hens and Wysolmerski Breast Cancer Research 2005 7:220 doi:10.1186/bcr1306 |
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