Table 3 |
||||
|
Details of the identified 37 predictive genes |
||||
|
Accession no. |
Gene similarity |
Putative cellular function |
Position ID |
Scorea |
|
|
||||
|
BC000514 |
Ribosomal protein L13a |
Ribosome production |
19AM |
0.8377 |
|
BC007512 |
Ribosomal protein L18a |
Ribosome production |
31AJ |
0.7321 |
|
BC019093 |
Guanine nucleotide binding protein, beta polypeptide 2-like; RACKs (receptors for activated C kinase) |
Protein translation |
12AM |
0.6972 |
|
BC009696 |
Interferon induced transmembrane protein 2 |
Cell – environment interaction, Immune response |
12Q |
-0.6962 |
|
BC047681 |
S100 calcium binding protein A9 (Calgranulin B) |
Defence; inhibition of casein kinase II |
31J |
-0.6444 |
|
BC066901 |
H3 histone, family 3B (H3.3B) |
Chromatin remodelling |
5AK |
-0.6394 |
|
BC034149 |
Ribosomal protein S3 |
Ribosome production |
23V |
0.639 |
|
AK026634 |
Highly similar to HUMTI227HC, mRNA for TI-227H |
- |
21AH |
0.627 |
|
BC047681 |
S100 calcium binding protein A9 (Calgranulin B) |
Defence; inhibition of casein kinase II |
24AQ |
-0.627 |
|
BC001126 |
Ribosomal protein S14 |
Ribosome production |
28T |
0.6231 |
|
NM_000980 |
Ribosomal protein L18a |
Ribosome production |
31AF |
0.6215 |
|
AY495316 |
Cytochrome c oxidase subunit, COX 1 |
Mitochondrial electron transport chain |
15AK |
0.6112 |
|
NM_001016 |
Ribosomal protein S12 |
Ribosome production |
22S |
0.6102 |
|
- |
- |
- |
20AG |
0.5839 |
|
BC016378 |
Ribosomal protein S11 |
Ribosome production |
8S |
0.5827 |
|
AY495316 |
Cytochrome c oxidase subunit, COX 1 |
Mitochondrial electron transport chain |
27AG |
0.5729 |
|
AF077043 |
Ribosomal protein L36 |
Ribosome production |
3AR |
0.5699 |
|
AF346981 |
Mitochondrial 16S rRNA |
Ribosome production |
25P |
0.5507 |
|
BC013857 |
H3 histone, family 3A |
Chromatin remodelling |
3T |
-0.5496 |
|
M22146 |
Ribosomal protein S4 |
Ribosome production |
31U |
0.5176 |
|
BC016857 |
Ferritin, heavy polypeptide 1 |
Iron storage; defence against ROS |
6N |
-0.5134 |
|
BC053370 |
Ribosomal protein SA |
Ribosome production |
2G |
0.5113 |
|
BC010165 |
Ribosomal protein S2 |
Ribosome production |
2V |
0.5071 |
|
BC009689 |
Cyclin D-type binding protein |
E2F-mediated transcription |
21O |
0.4978 |
|
BC018641 |
Eukaryotic translation elongation factor 1α (eEF1A) |
Protein translation |
4AA |
0.4974 |
|
D87735 |
Ribosomal protein L14 |
Ribosome production |
19H |
0.486 |
|
- |
- |
- |
6AQ |
0.4837 |
|
BC016857 |
Ferritin, heavy polypeptide 1 |
Iron storage; defence against ROS |
3AB |
-0.481 |
|
BC012146 |
Ribosomal protein L3 |
Ribosome production |
32AM |
0.4776 |
|
BC001126 |
Ribosomal protein S14 |
Ribosome production |
25R |
0.4759 |
|
BC006784 |
Ribosomal protein S14 |
Ribosome production |
24AJ |
0.4695 |
|
J03223 |
Human secretory granule proteoglycan peptide core |
Defence (may neutralize hydrolytic enzymes) |
11H |
-0.4681 |
|
AY147037 |
Myeloid/lymphoid or mixed-lineage leukemia 5 cDNA |
Chromatin remodeling and cellular growth suppression |
30AP |
0.4669 |
|
CD246392, EST |
Agencourt_14095501 NIH_MGC_172 cDNA |
- |
8AK |
0.4666 |
|
AY339570 |
Cytochrome c oxidase subunit, COX 1 |
Mitochondrial electron transport chain |
2E |
0.4662 |
|
U43701 |
Human ribosomal protein L23a |
Ribosome production |
8G |
0.4629 |
|
AY495252 |
Mitochondrial 16S rRNA |
Ribosome production |
8AF |
0.4625 |
|
|
||||
|
The position of genes in the array is shown as well as their scores, the accession number of sequences in public databases that match them, and their known or putative cellular function. aThe score is a shrunken t-statistic for comparing breast-cancer class to non-breast-cancer class. A positive score means that expression was greater in the noncancer sample than the cancer sample; a negative score means that expression was greater in the cancer sample than the noncancer sample. -, no information available; ROS, reactive oxygen species. |
||||
|
Sharma et al. Breast Cancer Research 2005 7:R634 doi:10.1186/bcr1203 |
||||
