|
Distribution of cells in the different cell cycle phases (%) and apoptotic cells (%) after different treatments |
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| MCF-7 |
BRC-230 |
|||||||
|
|
||||||||
| Treatment |
G1 |
S |
G2-M |
Apoptosis |
G1 |
S |
G2-M |
Apoptosis |
|
|
||||||||
| Untreated cells |
48 |
40 |
12 |
1 |
55 |
33 |
12 |
2 |
| Dox→Pacl |
6a |
14a |
80a |
22a |
10a |
27a |
63a |
15a |
| Dox→Pacl→48-h washout |
3a |
16a |
81a |
17a |
5a |
11a |
84a |
15a |
| Dox→Pacl→48-h washout→5-FU |
15a |
49 |
36a |
40a |
20a |
42a |
38a |
37a |
|
aP < 0.05 by t-test. 5-FU, 5-fluorouracil; Dox, doxorubicin; Pacl, paclitaxel. | ||||||||
Zoli et al. Breast Cancer Research 2005 7:R681 doi:10.1186/bcr1274 |
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