Table 2

Distribution of cells in the different cell cycle phases (%) and apoptotic cells (%) after different treatments

MCF-7

BRC-230


Treatment

G1

S

G2-M

Apoptosis

G1

S

G2-M

Apoptosis


Untreated cells

48

40

12

1

55

33

12

2

Dox→Pacl

6a

14a

80a

22a

10a

27a

63a

15a

Dox→Pacl→48-h washout

3a

16a

81a

17a

5a

11a

84a

15a

Dox→Pacl→48-h washout→5-FU

15a

49

36a

40a

20a

42a

38a

37a


aP < 0.05 by t-test. 5-FU, 5-fluorouracil; Dox, doxorubicin; Pacl, paclitaxel.

Zoli et al. Breast Cancer Research 2005 7:R681   doi:10.1186/bcr1274

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