Table 1 |
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Scoring system used to document cutaneous and subcutaneous reactions in breast cancer patients receiving radiotherapy |
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| Grade |
Early reactionsa |
Late reactionsb |
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| Grade 0 – Highly radioresistant patients |
No toxicity observed: no erythema, desquamation, or pain |
Absence of differences between irradiated and nonirradiated skin |
| Grade 1 – Moderately radioresistant patients |
Faint, dull, or bright erythema, psilosis, dry desquamation, mild oedema |
Minimal telangiectasia, slight breast asymmetry, mild hyperpigmentation |
| Grade 2 – Patients with average radiosensitivity |
Severe erythema, at least one moist desquamation of small size, moderate oedema |
Marked telangiectasia, moderate hyperpigmentation, increased density and palpable
firmness, mild oedema |
| Grade 3 – Moderately radiosensitive patients |
Severe or confluent moist desquamation |
Partially confluent telangiectasia, severe hyperpigmentation, severe oedema, subcutaneous
fibrosis with fixation |
| Grade 4 – Highly radiosensitive patients |
Ulceration, haemorrhage |
Totally confluent telangiectasia, very marked density, retraction and fixation. Major
aesthetic sequelae in treated breast |
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aMorbidity assessed at the end of radiotherapy treatment. bMorbidity assessed at end of 7-year follow-up period |
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López et al. Breast Cancer Research 2005 7:R690 doi:10.1186/bcr1277 |
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