Table 1 |
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|
Relations between proteina expression and clinicopathological characteristics in patients with breast cancer |
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| Characteristic |
Cks1 |
Skp2 |
p27Kip1 |
||||||
|
|
|||||||||
| High |
Low |
Pb |
High |
Low |
Pb |
High |
Low |
Pb |
|
|
|
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| Grade |
|||||||||
| 1 |
2 |
8 |
0.012 |
2 |
8 |
0.005 |
2 |
8 |
0.032 |
| 2 |
14 |
14 |
0.012 |
7 |
21 |
0.005 |
14 |
14 |
0.032 |
| 3 |
10 |
2 |
0.012 |
9 |
3 |
0.005 |
8 |
4 |
0.032 |
| Tumor sizec |
|||||||||
| T1 |
15 |
18 |
0.333 |
10 |
23 |
0.265 |
19 |
14 |
0.485 |
| T2 |
10 |
6 |
0.333 |
7 |
9 |
0.265 |
8 |
8 |
0.485 |
| T3 |
1 |
0 |
0.333 |
1 |
0 |
0.265 |
0 |
1 |
0.485 |
| Lymph node involvementc |
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| N0 |
16 |
15 |
0.508 |
11 |
20 |
0.803 |
18 |
13 |
0.387 |
| N1 |
6 |
3 |
0.508 |
4 |
5 |
0.803 |
3 |
6 |
0.387 |
| N2 |
4 |
6 |
0.508 |
3 |
7 |
0.803 |
6 |
4 |
0.387 |
| Estrogen receptor expression |
|||||||||
| Negative |
17 |
6 |
0.013 |
16 |
7 |
0.001 |
9 |
14 |
0.048 |
| Positive |
10 |
17 |
0.013 |
3 |
24 |
0.001 |
17 |
10 |
0.048 |
| Progesterone receptor expression |
|||||||||
| Negative |
15 |
3 |
0.006 |
14 |
4 |
0.001 |
5 |
13 |
0.032 |
| Positive |
12 |
20 |
0.006 |
4 |
27 |
0.001 |
20 |
12 |
0.032 |
| Age (years) |
|||||||||
| >50 |
14 |
5 |
0.017 |
12 |
7 |
0.002 |
7 |
12 |
0.051 |
| < 50 |
12 |
19 |
0.017 |
25 |
6 |
0.002 |
20 |
11 |
0.051 |
|
|
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|
aCks1, cyclin kinase subunit 1; p27Kip1, a cell-cycle inhibitory protein; Skp2, S-phase kinase protein 2. bRefers to the differences between protein expression and the variables. cAccording to the TNM (tumor, node, metastases) staging system of the American Joint Committee on Cancer. P ≤ 0.05 (values shown in bold type) was considered statistically significant. |
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|
Slotky et al. Breast Cancer Research 2005 7:R737 doi:10.1186/bcr1278 |
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